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  • Official Full Name

    T-box 22

  • Overview

    This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene have been associated with the inherited X-linked disorder, Cleft palate with ankyloglossia, and it is believed to play a major role in human palatogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    TBX22; T-box 22; cleft palate and/or ankyloglossia , CLPA, CPX; T-box transcription factor TBX22; T-box protein 22; CPX; CLPA; TBXX; dJ795G23.1;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TBX22-3142H Recombinant Human TBX22, GST-tagged E.coli GST C-term-330aa
Human TBX22-1200HCL Recombinant Human TBX22 293 Cell Lysate HEK293 N/A
Zebrafish TBX22-7577Z Recombinant Zebrafish TBX22 Mammalian Cell His
Chicken TBX22-5682C Recombinant Chicken TBX22 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

TBX22 involved in several pathways and played different roles in them. We selected most pathways TBX22 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TBX22 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

TBX22 has several biochemical functions, for example, DNA binding, protein binding, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TBX22 itself. We selected most functions TBX22 had, and list some proteins which have the same functions with TBX22. You can find most of the proteins on our site.

Function Related Protein
protein bindingAPOO;MASP2;NAB2;MT1A;GNA14;HGS;HLA-A;MKI67;TIMM21
transcription factor activity, sequence-specific DNA bindingNFE2L2;ALX3;HOXC8A;NFAT5;SOX5;HLFB;FOXN3;LHX1A;MEOX1

TBX22 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TBX22 here. Most of them are supplied by our site. Hope this information will be useful for your research of TBX22.

VENTX; HSP90AB1; STIP1; q96be0_human

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