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TBX6

Official Full Name

T-box 6
Overview

This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Knockout studies in mice indicate that this gene is important for specification of paraxial mesoderm structures. [provided by RefSeq, Aug 2008]
Synonyms

TBX6; T-box 6; SCDO5; T-box transcription factor TBX6; T-box protein 6;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rat
Zebrafish

Source

HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	TBX6-656HCL	Recombinant Human TBX6 lysate	HEK293	N/A	Inquiry
Mouse	TBX6-16535M	Recombinant Mouse TBX6 Protein	Mammalian Cell	His	Inquiry
Mouse	TBX6-9064M-B	Recombinant Mouse TBX6 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Mouse	TBX6-9064M	Recombinant Mouse TBX6 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rat	TBX6-5977R	Recombinant Rat TBX6 Protein	Mammalian Cell	His	Inquiry
Rat	TBX6-5636R	Recombinant Rat TBX6 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rat	TBX6-5636R-B	Recombinant Rat TBX6 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Zebrafish	TBX6-8680Z	Recombinant Zebrafish TBX6	Mammalian Cell	His	Inquiry
Chicken	TBX6-2238C	Recombinant Chicken TBX6	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

TBX6 involved in several pathways and played different roles in them. We selected most pathways TBX6 participated on our site, such as Neural Crest Differentiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with TBX6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Neural Crest Differentiation	FOXD3;DMBX1;MBP;CTBP2;OLIG3;HOXA1;LHX2;TCF4;PRTG

TBX6 has several biochemical functions, for example, DNA binding, RNA polymerase II activating transcription factor binding, RNA polymerase II transcription factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TBX6 itself. We selected most functions TBX6 had, and list some proteins which have the same functions with TBX6. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	ILF2;TEAD1;TRP63;ZFAND5B;TERF1;NKX2;SUPV3L1;PLAGL1;RPAP1
RNA polymerase II activating transcription factor binding	EP300;POU1F1;NFE2L2;SETD3;ZFPM1;BEX1;MAD2L2;TBX6;JUN
RNA polymerase II transcription factor binding	TEAD3;GATA5;ZFPM2A;WWP2;TBX20;KLF4;MTA2;MIXL1;MTDH
protein binding	PIR;FURIN;BSCL2;TDRKH;SAMM50;SCARF1;FRS3;KRT79;TMPO
transcription factor activity, sequence-specific DNA binding	HOXA13;RNF4;AHCTF1;NKX3;SPI1B;EGR2;LZTS1;CBFA2T2;THRA
transcriptional repressor activity, RNA polymerase II transcription factor binding	AHRR;ELP2;EOMES;TBX6;AHRRB;PITX2;T;RIMKLB;BHLHE40

TBX6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TBX6 here. Most of them are supplied by our site. Hope this information will be useful for your research of TBX6.

TOX4; C1orf94; RBPMS; HSFY1; lepA; PRMT1