TBX6
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Official Full Name
T-box 6
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Overview
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Knockout studies in mice indicate that this gene is important for specification of paraxial mesoderm structures. [provided by RefSeq, Aug 2008] -
Synonyms
TBX6; T-box 6; SCDO5; T-box transcription factor TBX6; T-box protein 6;
- Cell & Tissue Lysates
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Zebrafish
- HEK293
- Mammalian Cell
- His
- Fc
- Avi
- Non
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | TBX6-656HCL | Recombinant Human TBX6 lysate | HEK293 | Non |
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| Mouse | TBX6-16535M | Recombinant Mouse TBX6 Protein | Mammalian Cell | His |
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| Mouse | TBX6-9064M-B | Recombinant Mouse TBX6 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Mouse | TBX6-9064M | Recombinant Mouse TBX6 Protein, His (Fc)-Avi-tagged | HEK293 | His&Fc&Avi |
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| Rat | TBX6-5977R | Recombinant Rat TBX6 Protein | Mammalian Cell | His |
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| Rat | TBX6-5636R | Recombinant Rat TBX6 Protein, His (Fc)-Avi-tagged | HEK293 | His&Fc&Avi |
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| Rat | TBX6-5636R-B | Recombinant Rat TBX6 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Zebrafish | TBX6-8680Z | Recombinant Zebrafish TBX6 | Mammalian Cell | His |
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| Chicken | TBX6-2238C | Recombinant Chicken TBX6 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
TBX6 involved in several pathways and played different roles in them. We selected most pathways TBX6 participated on our site, such as Neural Crest Differentiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with TBX6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Neural Crest Differentiation | TBX6;MBP;TFAP2B;LHX2;DMBX1;CTBP2;LHX1;SOX5;GBX2 |
TBX6 has several biochemical functions, for example, DNA binding, RNA polymerase II activating transcription factor binding, RNA polymerase II transcription factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TBX6 itself. We selected most functions TBX6 had, and list some proteins which have the same functions with TBX6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | DMRT3A;ZNF19;CHES1;DHARMA;FOXE1;ZFP1;RAD51AP1;CENPW;ZNF280D |
| RNA polymerase II activating transcription factor binding | EP300;ISL1;HIPK2;EGR2;NHLH2;SMAD3;HNF4A;LMO2;SETD3 |
| RNA polymerase II transcription factor binding | MTA2;TBX6;GATA3;ANKRD1;GATA6;DHX9;GATA1A;TP53;ZGLP1 |
| protein binding | RAB2B;TCEB3;MYL6B;PAX5;BTBD1;IMPDH2;CDH1;MUC5B;FCN3 |
| transcription factor activity, sequence-specific DNA binding | ZKSCAN1;ONECUT3;NFIL3;SP140;TBR1;FOXD3;ATF6;HOXC6A;WT1B |
| transcriptional repressor activity, RNA polymerase II transcription factor binding | TBX6;BHLHE40;MLIP;CREBBP;AHRRB;T;ELP2;PITX2;AHRR |
TBX6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TBX6 here. Most of them are supplied by our site. Hope this information will be useful for your research of TBX6.
TOX4; C1orf94; RBPMS; HSFY1; lepA; PRMT1
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