Recombinant Human TGFB3 Protein
Cat.No. : | TGFB3-38H |
Product Overview : | Recombinant human TGF-β3 protein without tag was expressed in E. coli. Animal-free (AOF) and carrier protein-free. Mass spectrometry: single species with expected mass. Recovery from stock vial: >95% |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic right ventricular dysplasia 1. |
Source : | E. coli |
Species : | Human |
Molecular Mass : | 12.7 kDa monomer, 25.4 kDa dimer |
Endotoxin : | <0.005 EU/μg protein (below level of detection) |
Applications : | Chemically defined media for organoid culture |
Storage : | Resuspend in 10mM HCl (Reconstitution solution A) at >100 μg/mL, prepare single use aliquots, add carrier protein if desired and store frozen at -20 or -80 centigrade |
Storage Buffer : | Lyophilized from acetonitrile, TFA |
Gene Name : | TGFB3 transforming growth factor beta 3 [ Homo sapiens (human) ] |
Official Symbol : | TGFB3 |
Synonyms : | TGFB3; transforming growth factor beta 3; ARVD; LDS5; RNHF; ARVD1; TGF-beta3; transforming growth factor beta-3 proprotein; prepro-transforming growth factor beta-3 |
Gene ID : | 7043 |
mRNA Refseq : | NM_001329938 |
Protein Refseq : | NP_001316867 |
MIM : | 190230 |
UniProt ID : | P10600 |
Products Types
◆ Recombinant Protein | ||
TGFB3-246H | Active Recombinant Human/Mouse TGFB3 Protein | +Inquiry |
TGFB3-48H | Active Recombinant Human TGFB3 Protein, Animal Free | +Inquiry |
TGFB3-4502R | Recombinant Rhesus Macaque TGFB3 Protein, His (Fc)-Avi-tagged | +Inquiry |
TGFB3-245H | Active Recombinant Human/Mouse TGFB3 Protein | +Inquiry |
TGFB3-105H | Active Recombinant Human TGFB3 Protein | +Inquiry |
◆ Lysates | ||
TGFB3-1118HCL | Recombinant Human TGFB3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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