| Species : |
Human/Mouse |
| Source : |
E.coli |
| Description : |
Transforming growth factors (TGFs) are multifunctional peptides that regulate growth and differentiation in most cell types. The TGF-β family of proteins signal through serine/threonine kinase receptors. TGF-β isoforms (TGF-β1, -β2, and –β3) have overlapping, yet distinct biological actions in developing and adult tissues. TGF-β3 is an important factor in regulating cell adhesion and accelerating wound repair. TGF-β3 also functions during osteoblast proliferation, chemotaxis, and collagen synthesis. |
| Bio-activity : |
Inhibition of IL-4-induced HT-2 cell proliferation, ≤1 ng/mL |
| Molecular Mass : |
Dimer, 12.9/25.7 kDa (113/226 aa) |
| AA Sequence : |
MALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS |
| Endotoxin : |
≤1 EUs/μg, Kinetic LAL |
| Purity : |
≥95%, Reducing and Non-Reducing SDS PAGE |
| Stability : |
12 months from date of receipt when stored at 4 centigrade as supplied. |
| Storage : |
Storage: Centrifuge vial before opening. DO NOT VORTEX. Store at 4 centigrade. |
| Concentration : |
0.25 mg/mL |
| Storage Buffer : |
In solution: 10 mM acetic acid and 20% Ethanol |
| Shipping : |
Ice pack |
