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Recombinant Pig TGFB3 protein, His & T7-tagged

Cat.No. : TGFB3-2004P
Product Overview : Recombinant Pig TGFB3 aa. (Ala298~Ser409 (Accession # P15203)) fused with N-terminal His & T7 tag was produced in E. coli cells.
  • Specification
  • Gene Information
  • Related Products
Source : E. coli
Species : Pig
Tag : His & T7
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 16.4kDa
Protein length : Ala298~Ser409 (Accession # P15203)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >90%
Characteristic : The isoelectric point is 6.1.
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage Buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : TGFB3 transforming growth factor beta 3 [ Sus scrofa (pig) ]
Official Symbol : TGFB3
Synonyms : Ptpn22; protein tyrosine phosphatase, non-receptor type 22; Ptpn8; tyrosine-protein phosphatase non-receptor type 22; protein tyrosine phosphatase, non-receptor type 22 (lymphoid); protein tyrosine phosphatase, non-receptor type 8
Gene ID : 397400
mRNA Refseq : NM_214198.1
Protein Refseq : NP_999363.1
UniProt ID : P15203

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Is there a treatment for TGFB3? 12/16/2019

Currently, researchers are exploring treatments that target TGFB3. Several drugs and antibodies have shown potential efficacy against TGFB3 and are being used in clinical trials for the treatment of the disease.

How does TGFB3 participate in cell proliferation? 08/27/2019

TGFB3 can regulate cell proliferation by activating multiple signaling pathways, such as the Smad signaling pathway and non-Smad signaling pathway. It can promote the progression of the cell cycle or inhibit cell proliferation, depending on the cell type and context.

What are the applications of TGFB3 protein in clinical diagnosis? 07/25/2019

TGFB3 protein can be used as a biomarker to assist the clinical diagnosis of a variety of diseases, such as congenital developmental abnormalities, inflammatory diseases and fibrotic diseases. Measuring TGFB3 protein levels can provide an indicator of early diagnosis and prognostic assessment of disease.

Are there any genetic diseases associated with TGFB3? 06/23/2019

Mutations in TGFB3 have been found to be associated with inherited connective tissue diseases such as Loeys-Dietz syndrome and Marfan syndrome.

Is TGFB3 potentially used to treat pulmonary fibrosis? 05/25/2019

In pulmonary fibrosis, the expression of TGFB3 is elevated and is involved in the development of pulmonary fibrosis. Due to its important role in the pathological process, inhibition of the TGFB3 signaling pathway may be a potential strategy for the treatment of pulmonary fibrosis.

How is TGFB3 related to the immune system? 04/13/2019

TGFB3 plays an important regulatory role in the immune system. It can influence the immune response through the proliferation, differentiation, and functional regulation of immune cells.

Customer Reviews (3)

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Reviews
12/08/2019

    Reproducibility is very good, and the results are very consistent in each experiment or application, making it ideal for experiments or applications that require a high degree of reproducibility.

    10/13/2019

      Their recombinant proteins are very soluble and can be easily dissolved in various buffers.

      05/19/2019

        Catalytic activity of this protein is very high, which can greatly reduce the time and energy required for chemical reactions and has high economic value.

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