Recombinant Human Transforming Growth Factor, Beta 3, Dimeric Form

• Cat.No.: TGFB3-006N
• Product Overview: It is produced by transient expression of TGFβ-3 in non-transgenic plant. Recombinant human TGFβ-3 is purified by sequential chomatograpy (FPLC). This product contains no anim –derived components or impurities.

Specification

• Species: Human
• Source: Nicotiana Benthamiana
• Tag: Non
• Description: Transforming growth factor-beta 3 (TGF-beta 3) is a member of the TGF beta family of growth factors. It is involved in oxygen-dependent differentiation processes during placental development and pregnancy disorders. It also play an important role in wound repair and scarring.
• Formulation: Lyophilized from a buffer of Tris HCl 0.05M pH 7.4.
• Molecularformula: C600H902N166O174S10
• Extinction coefficient: E0.1% = 1.729 (A280 nm).
• Molecular weight: 25.4 kDa
• p.l: 6.75
• Purityassay: >95 % as determinate by SDS-PAGE gel.
• Endotoxin level: < 0.04 EU/ μg protein (LAL method).
• Biological Activity: The biological activity of TGF-β3 is measured in culture by its ability to inhibit the mink lung epithelial cells proliferation. (ED50 is defined as the effective concentration of growth factor that elicits a 50% inhibition in cell growth in a cell based bioassay)
• Storage: This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage. Repeated freezing and thawing is not recommended.

Gene Information

• Gene Name: TGFB3 transforming growth factor, beta 3 [ Homo sapiens ]
• Official Symbol: TGFB3
• Synonyms: Transforming Growth Factor-beta3; TGFB3; ARVD; FLJ16571; TGF-beta3; transforming growth factor, beta 3
• Gene ID: 7043
• mRNA Refseq: NM_003239
• Protein Refseq: NP_003230
• MIM: 190230
• UniProt ID: P10600
• Chromosome Location: 14q24
• Function: Growth factor activity; Identical protein binding; Protein heterodimerization activity; Transforming growth factor beta binding; Type I transforming growth factor beta receptor binding; Type II transforming growth factor beta receptor binding