TGFBR3 Protein

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TGFBR3

Official Full Name	transforming growth factor, beta receptor III
Background	This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Synonyms	TGFBR3; transforming growth factor, beta receptor III; transforming growth factor, beta receptor III (betaglycan, 300kDa); transforming growth factor beta receptor type 3; betaglycan; betaglycan proteoglycan; BGCAN; TGFR-3; TGF-beta receptor type 3; TGF-b

Species :
Chicken
Human
Mouse
Rat

Source :
E.coli
HEK293
Human Cell
Insect Cell
Mammalian Cell
Mammalian cells

Tag :
His
GST
N/A

Species	Cat.#	Product name	Source (Host)	Tag
Human	TGFBR3-1685H	Recombinant Human Transforming Growth Factor, Beta Receptor III	Mammalian cells	N/A
Human	TGFBR3-193H	Recombinant Human TGFBR3	Mammalian cells	N/A
Human	TGFBR3-340H	Recombinant Human TGFBR3, His tagged	Insect Cell	His
Human	TGFBR3-698H	Recombinant Human TGFBR3, His-tagged, Biotinylated	Human Cell	His
Human	TGFBR3-699H	Recombinant Human TGFBR3, His-tagged	Human Cell	His
Mouse	Tgfbr3-658M	Recombinant Mouse Tgfbr3 Protein, His-tagged	Mammalian cells	His
Mouse	Tgfbr3-7042M	Recombinant Mouse Tgfbr3, His tagged	Human Cell	His
Rat	TGFBR3-6040R	Recombinant Rat TGFBR3 Protein	Mammalian Cell	His
Chicken	TGFBR3-5911C	Recombinant Chicken TGFBR3	Mammalian Cell	His
Human	TGFBR3-001HCL	Recombinant Human TGFBR3 cell lysate	Insect Cell	N/A
Mouse	TGFBR3-1847MCL	Recombinant Mouse TGFBR3 cell lysate	Human Cell	N/A
Mouse	Tgfbr3-705M	Recombinant Mouse Tgfbr3(Gly23-Thr785) Protein, C-6*His-tagged	HEK293	His
Mouse	Tgfbr3-297M	Recombinant Mouse Tgfbr3 Protein, His/GST-tagged	E.coli	His/GST
Rat	Tgfbr3-298R	Recombinant Rat Tgfbr3 Protein, His-tagged	E.coli	His

Involved Pathway Protein Function Interacting Protein TGFBR3 Related Gene Family

TGFBR3 involved in several pathways and played different roles in them. We selected most pathways TGFBR3 participated on our site, such as TGF Beta Signaling Pathway, TGF-beta Receptor Signaling Pathway, TGF-beta receptor signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with TGFBR3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
TGF Beta Signaling Pathway	FST; TGFBR3; LEFTY1; ENG; ZNF423; RUNX3; NOG; ZFP423; FOXH1
TGF-beta Receptor Signaling Pathway	ENG; TGFBR3; DAB2; FOXH1; ACVRL1; ZEB1B; EID2; JUNBA; GIPC1; ZEB2A
TGF-beta receptor signaling	DAB2; EIF2A; TGFBR3; STRAP

TGFBR3 has several biochemical functions, for example, PDZ domain binding, SMAD binding, activin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TGFBR3 itself. We selected most functions TGFBR3 had, and list some proteins which have the same functions with TGFBR3. You can find most of the proteins on our site.

Function	Related Protein
PDZ domain binding	BAIAP2; ATP2B2; SNTB1; TBC1D10A; GIPC1; LLGL2; LNX1; LIN7C; GRM7; PLEKHA1
SMAD binding	SOD3; YY1; SKI; CTNNB1; DAB2; SNW1; COL3A1; SKOR1B; TCF12; FLNA
activin binding	TGFBR3; ENG; SMAD7; FKBP1A; FSTL3; ACVR2B; ACVR1; FST; ACVRL1; SMURF1
coreceptor activity	CD80; RAMP3; CXCR7B; LY96; CCR5; TGFBR3; RAMP2; PVRL2; CD8A; ACKR3B
fibroblast growth factor binding	FIBP; FIBPB; HSPA9; CEP57; GLG1; PTPRZ1; CXCL13; FIBPA; FGFR1A; GPC1
glycosaminoglycan binding	SPOCK2; NDNF; Shh; TGFBR3; ENG; CCDC80; VIT; DCN; SPOCK3; PODXL2
heparin binding	GREM2; CXCL10; CTGFB; SERPINA10; CYR61; SERPINA5; SERPIND1; PGF; ZNF207; WISP1B
protein binding	MYCBP; C12orf68; DTD2; LIMD2; C10orf35; POU3F3; POU4F1; STRN; SNRPD3; PSMD3
contributes_to protein binding	MEF2A; POLR2A; INHA; MSH2; ACVR2A; MLH1; CRY1A; TAF10; CPSF3L; PAK1
transforming growth factor beta binding	LTBP4; HYAL2; ITGAV; TGFBR1; CD109; ENG; LTBP1; TGFBR3; TGFBR2; TGFB3
contributes_to transforming growth factor beta binding	TGFBR1; TGFBR2; ENG; TGFBR3
transforming growth factor beta receptor activity, type III	TGFBR3
transforming growth factor beta receptor binding	BMP10; NDR2; GDF9; GDF2; GDF10; INHBC; BMP8A; GDF1; INHBAB; LEFTY2
transforming growth factor beta-activated receptor activity	BMPR2A; TGFBR3; TGFBR2; TGFBR1; LTBP1; ENG; ACVRL1; BMPR2B
type II transforming growth factor beta receptor binding	TGFB2; TGFB1; BAMBI; TGFB3; TGFB1A; TGFBR3; TGFBR1; ENG

TGFBR3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TGFBR3 here. Most of them are supplied by our site. Hope this information will be useful for your research of TGFBR3.

GIPC1; TGFB1; TGFB3; cutF

TGFBR3

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TGFBR3

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