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Official Full Name transforming growth factor, beta receptor III
Background This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Synonyms TGFBR3; transforming growth factor, beta receptor III; transforming growth factor, beta receptor III (betaglycan, 300kDa); transforming growth factor beta receptor type 3; betaglycan; betaglycan proteoglycan; BGCAN; TGFR-3; TGF-beta receptor type 3; TGF-b
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Insect Cell
    • Mammalian Cell
    • Mammalian cells
    • Tag :
    • His
    • GST
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Tgfbr3-705M Recombinant Mouse Tgfbr3(Gly23-Thr785) Protein, C-6*His-tagged HEK293 His
    Human TGFBR3-001HCL Recombinant Human TGFBR3 cell lysate Insect Cell N/A
    Human TGFBR3-1685H Recombinant Human Transforming Growth Factor, Beta Receptor III Mammalian cells N/A
    Human TGFBR3-193H Recombinant Human TGFBR3 Mammalian cells N/A
    Human TGFBR3-340H Recombinant Human TGFBR3, His tagged Insect Cell His
    Human TGFBR3-698H Recombinant Human TGFBR3, His-tagged, Biotinylated Human Cell His
    Human TGFBR3-699H Recombinant Human TGFBR3, His-tagged Human Cell His
    Mouse TGFBR3-1847MCL Recombinant Mouse TGFBR3 cell lysate Human Cell N/A
    Mouse Tgfbr3-297M Recombinant Mouse Tgfbr3 Protein, His/GST-tagged E.coli His/GST
    Mouse Tgfbr3-658M Recombinant Mouse Tgfbr3 Protein, His-tagged Mammalian cells His
    Mouse Tgfbr3-7042M Recombinant Mouse Tgfbr3, His tagged Human Cell His
    Rat Tgfbr3-298R Recombinant Rat Tgfbr3 Protein, His-tagged E.coli His
    Rat TGFBR3-6040R Recombinant Rat TGFBR3 Protein Mammalian Cell His
    Chicken TGFBR3-5911C Recombinant Chicken TGFBR3 Mammalian Cell His

    TGFBR3 involved in several pathways and played different roles in them. We selected most pathways TGFBR3 participated on our site, such as TGF Beta Signaling Pathway, TGF-beta Receptor Signaling Pathway, TGF-beta receptor signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with TGFBR3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    TGF Beta Signaling Pathway FOXH1; TGFBR3; FST; RUNX3; ZFP423; ENG; ZNF423; LEFTY1; NOG
    TGF-beta Receptor Signaling Pathway NFYBB; RUNX2A; VDRB; CITED1; FOXH1; EID2; DAB2; STAMBPL1; COPS5; SNIP1
    TGF-beta receptor signaling STRAP; DAB2; TGFBR3; EIF2A

    TGFBR3 has several biochemical functions, for example, PDZ domain binding, SMAD binding, activin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TGFBR3 itself. We selected most functions TGFBR3 had, and list some proteins which have the same functions with TGFBR3. You can find most of the proteins on our site.

    Function Related Protein
    PDZ domain binding ERC1; KIDINS220B; ARHGEF16; ATP2B1A; ATP2B1B; LNX1; GRIK5; LIN7B; GRIA1; ARHGAP29
    activin binding FSTL3; ACVR1; SMURF1; ENG; TGFBR3; FST; ACVR2B; FKBP1A; ACVRL1; SMAD7
    coreceptor activity LRP5; RAMP3; LY96; CD80; PVRL1; NRP1; CD8B; CCR8; ACKR3B; HFE2
    fibroblast growth factor binding FIBPB; GPC1; FGFR3; FGFRL1; RPS19; CXCL13; S100A13; FIBPA; FIBP; FGFR4
    glycosaminoglycan binding PODXL2; ENG; VCAN; SPOCK3; HABP2; SERPINE2; TGFBR3; BGN; NDNF; SPOCK2
    heparin binding SAA1; RSPO4; LIPG; RPL22; WISP1; FGFR1; NOV; FMOD; NRP1; ELANE
    protein binding PVRL3; MYOD1; CD151; ZNF224; FBXO45; FYCO1; USHBP1; SCAF8; AKAP7; TES
    contributes_to protein binding INTS10; MLH1; MSH2; TGFBR3; ACVR2A; POLR2A; PAK1; MEF2A; TAF10; CRY1A
    transforming growth factor beta binding TGFB3; TGFBR2; LTBP1; ITGAV; THBS1; ACVR1; LTBP4; HYAL2; TGFBR3; ACVRL1
    contributes_to transforming growth factor beta binding TGFBR2; TGFBR3; ENG; TGFBR1
    transforming growth factor beta receptor activity, type III TGFBR3
    transforming growth factor beta receptor binding GDF6B; GDF10; TGFB2; GDF2; SPAW; NODAL; SMURF2; LRG1; BMP8A; BMP2
    transforming growth factor beta-activated receptor activity ENG; TGFBR1; LTBP1; BMPR2B; ACVRL1; TGFBR3; TGFBR2; BMPR2A
    type II transforming growth factor beta receptor binding TGFB1A; TGFB2; TGFB1; TGFBR1; TGFB3; ENG; TGFBR3; BAMBI

    TGFBR3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TGFBR3 here. Most of them are supplied by our site. Hope this information will be useful for your research of TGFBR3.

    GIPC1; TGFB1; TGFB3; cutF


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