Recombinant Mouse Tgfbr3 Protein, His (Fc)-Avi-tagged

• Cat.No.: Tgfbr3-9163M
• Product Overview: Recombinant Mouse Tgfbr3 with His (Fc)-Avi tag was expressed and purified

Specification

• Source: HEK293
• Species: Mouse
• Tag: His&Fc&Avi
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: ≥85% by SDS-PAGE
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: Tgfbr3 transforming growth factor, beta receptor III [ Mus musculus ]
• Official Symbol: Tgfbr3
• Synonyms: TGFBR3; transforming growth factor, beta receptor III; transforming growth factor beta receptor type 3; TGFR-3; betaglycan; TGF-beta receptor type 3; TGF-beta receptor type III; TBRIII; AU015626; AW215636; 1110036H20Rik
• Gene ID: 21814
• mRNA Refseq: NM_011578
• Protein Refseq: NP_035708

Reviews

05/10/2022

Great product !

02/18/2020

Seamless delivery process—ordered, received, and ready for experiments.

08/31/2018

Timely delivery is key, and this product arrived on schedule.

Q&As

What are the implications of TGFBR3 mutations in the context of hereditary connective tissue disorders?

TGFBR3 mutations are associated with hereditary connective tissue disorders, impacting extracellular matrix homeostasis and contributing to conditions like Loeys-Dietz syndrome.

How does TGFBR3 influence embryonic development, and what are the consequences of its dysregulation during development?

TGFBR3 plays a role in embryonic development, and dysregulation may lead to developmental abnormalities due to disrupted TGF-beta signaling.

Can you explain the role of TGFBR3 in mediating interactions between cells and extracellular matrix components?

TGFBR3 facilitates cell-ECM interactions by modulating TGF-beta signaling, influencing processes like cell adhesion and migration.

How does TGFBR3 contribute to the modulation of TGF-beta signaling pathways?

TGFBR3 acts as a co-receptor, enhancing the binding of TGF-beta ligands to TGF-beta receptors, and modulates downstream signaling events.

What are the functional consequences of TGFBR3 mutations in the context of cardiovascular diseases?

TGFBR3 mutations are implicated in cardiovascular diseases, affecting TGF-beta-mediated processes in vascular smooth muscle cells and cardiac tissues.