Recombinant Rat Tgfbr3 Protein, His-tagged

Cat.No. : Tgfbr3-298R
Product Overview : Recombinant Rat Tgfbr3(Asn210~Ala465) fused with His tag at N-terminal was expressed in E. coli.
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Source : E. coli
Species : Rat
Tag : His
Form : PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Molecular Mass : 32.6kDa
Protein length : Asn210~Ala465
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : > 95%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution : Reconstitute in PBS or others
FACS:
Gene Name : Tgfbr3 transforming growth factor, beta receptor III [ Rattus norvegicus ]
Official Symbol : Tgfbr3
Synonyms : TGFBR3; transforming growth factor, beta receptor III; transforming growth factor beta receptor type 3; TGFR-3; TGF-beta receptor type 3; TGF-beta receptor type III; transforming growth factor, beta receptor 3; betaglycan;
Gene ID : 29610
mRNA Refseq : NM_017256
Protein Refseq : NP_058952
UniProt ID : P26342

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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What are the implications of TGFBR3 mutations in the context of hereditary connective tissue disorders? 03/05/2022

TGFBR3 mutations are associated with hereditary connective tissue disorders, impacting extracellular matrix homeostasis and contributing to conditions like Loeys-Dietz syndrome.

How does TGFBR3 influence embryonic development, and what are the consequences of its dysregulation during development? 04/26/2021

TGFBR3 plays a role in embryonic development, and dysregulation may lead to developmental abnormalities due to disrupted TGF-beta signaling.

Can you explain the role of TGFBR3 in mediating interactions between cells and extracellular matrix components? 07/15/2019

TGFBR3 facilitates cell-ECM interactions by modulating TGF-beta signaling, influencing processes like cell adhesion and migration.

How does TGFBR3 contribute to the modulation of TGF-beta signaling pathways? 05/24/2018

TGFBR3 acts as a co-receptor, enhancing the binding of TGF-beta ligands to TGF-beta receptors, and modulates downstream signaling events.

What are the functional consequences of TGFBR3 mutations in the context of cardiovascular diseases? 02/11/2018

TGFBR3 mutations are implicated in cardiovascular diseases, affecting TGF-beta-mediated processes in vascular smooth muscle cells and cardiac tissues.

Customer Reviews (3)

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Reviews
05/10/2022

    Great product !

    02/18/2020

      Seamless delivery process—ordered, received, and ready for experiments.

      08/31/2018

        Timely delivery is key, and this product arrived on schedule.

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