TLL2

  • Official Full Name

    tolloid-like 2
  • Synonyms

    TLL2;tolloid-like 2;11844;ENSG00000095587;10q23-q24;KIAA0932, MGC133312, MGC133313;tolloid-like protein 2;tolloid-like protein 2
Cat.# Product name Source (Host) Species Tag Protein Length Price
TLL2-3255H Recombinant Human TLL2, His-tagged E.coli Human His 67-154aa
TLL2-1048HCL Recombinant Human TLL2 293 Cell Lysate HEK293 Human Non
TLL2-3256H Recombinant Human TLL2 Protein, GST-tagged Wheat Germ Human GST 1-1015
Tll2-453M Recombinant Mouse Tll2 protein, His&Myc-tagged E.coli Mouse His&Myc 146-346a.a.
Tll2-785M Recombinant Mouse Tll2 protein, His-tagged E.coli Mouse His 146-346a.a.

    Involved Pathway

    TLL2 involved in several pathways and played different roles in them. We selected most pathways TLL2 participated on our site, such as Anchoring fibril formation,Assembly of collagen fibrils and other multimeric structures,Collagen biosynthesis and modifying enzymes, which may be useful for your reference. Also, other proteins which involved in the same pathway with TLL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Crosslinking of collagen fibrils LOXL4,ABHD1,BMP1B,LOXL1,PCOLCE,TLL1,LOX,LOXL3,BMP1,BMP1A
    Degradation of the extracellular matrix TIMP2B,BMP1A,COL17A1,FAM49BA,ADAM9,CTS7,MMP17,ACAN,ADAMTS5,CTSD
    Collagen formation LOXL4,P3H2,COL8A1,COL4A4,COL1A1,COL5A2,COL4A6,EMID2,PPIB,COL4A3
    Extracellular matrix organization BGNA,F11R.2,CMA1,COL5A2,ABHD1,MMP12,PCOLCE2,COL9A1A,MFAP1B,LAMC3
    Assembly of collagen fibrils and other multimeric structures COL8A1A,ABHD1,COL5A1,CTSL2,COL5A3A,LOXL3,LOXL2,LOXL4,COL3A1,COL6A3
    Anchoring fibril formation BMP1,BMP1B,TLL1,BMP1A
    Collagen biosynthesis and modifying enzymes BMP1A,COL4A4,COL4A3,COL9A1B,BMP1B,COL19A1,SERPINH1B,PCOLCEB,COL5A3B,COL8A1A

    Protein Function

    TLL2 has several biochemical functions, for example, calcium ion binding,metalloendopeptidase activity,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TLL2 itself. We selected most functions TLL2 had, and list some proteins which have the same functions with TLL2. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding PCDH2AB9,PVALB,PLCB1,LDLRB,CABP4,SNCB,CANT1B,VCAN,PCDH2AB1,CAPRIN1A
    zinc ion binding CRYZL1,MMP11,MKRN3,MIB1,LASP1,BHMT2,RNF115,ADAM5,ZFML,CA1
    metalloendopeptidase activity MBTPS2,ADAMTS9,UQCRC2,MMP11,PAPPAB,ADAMTS5,MMP30,ADAM30,UQCRC2B,MMP15

    Interacting Protein

    TLL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TLL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TLL2.

    Resources

    References

    • Cvjeticanin, B; Prutki, M; et al. Possible target for preventing fibrotic scar formation following acute myocardial infarction. MEDICAL HYPOTHESES 83:656-658(2014).
    • Malecaze, F; Massoudi, D; et al. Upregulation of Bone Morphogenetic Protein-1/Mammalian Tolloid and Procollagen C-Proteinase Enhancer-1 in Corneal Scarring. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 55:-(2014).

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