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TMEM127

Official Full Name

transmembrane protein 127
Overview

This gene encodes a transmembrane protein with 3 predicted transmembrane domains. The protein is associated with a subpopulation of vesicular organelles corresponding to early endosomal structures, with the Golgi, and with lysosomes, and may participate in protein trafficking between these structures. Mutations in this gene and several other genes cause pheochromocytomas. Alternatively spliced transcript variants encoding the same protein have been identified.
Synonyms

TMEM127; transmembrane protein 127; FLJ20507; FLJ22257;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Danio rerio (Zebrafish) (Brachydanio rerio)
Homo sapiens (Human)
Mouse
Mus musculus (Mouse)
Rhesus Macaque
Zebrafish

Source

E.coli expression system
HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Mouse	TMEM127-16905M	Recombinant Mouse TMEM127 Protein	Mammalian Cell	His		Inquiry
Mouse	TMEM127-9288M-B	Recombinant Mouse TMEM127 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	TMEM127-9288M	Recombinant Mouse TMEM127 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Danio rerio (Zebrafish) (Brachydanio rerio)	RFL8585DF	Recombinant Full Length Danio Rerio Transmembrane Protein 127(Tmem127) Protein, His-Tagged	E.coli expression system	His	Full Length (1-237)	Inquiry
Homo sapiens (Human)	RFL23143HF	Recombinant Full Length Human Transmembrane Protein 127(Tmem127) Protein, His-Tagged	E.coli expression system	His	Full Length (1-238)	Inquiry
Mus musculus (Mouse)	RFL11190MF	Recombinant Full Length Mouse Transmembrane Protein 127(Tmem127) Protein, His-Tagged	E.coli expression system	His	Full Length (1-238)	Inquiry
Rhesus Macaque	TMEM127-4771R	Recombinant Rhesus monkey TMEM127 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	TMEM127-4585R-B	Recombinant Rhesus Macaque TMEM127 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	TMEM127-4585R	Recombinant Rhesus Macaque TMEM127 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Zebrafish	TMEM127-2719Z	Recombinant Zebrafish TMEM127	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
TMEM127 Related Articles

TMEM127 involved in several pathways and played different roles in them. We selected most pathways TMEM127 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TMEM127 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

TMEM127 has several biochemical functions, for example, Rab GTPase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TMEM127 itself. We selected most functions TMEM127 had, and list some proteins which have the same functions with TMEM127. You can find most of the proteins on our site.

Function	Related Protein
Rab GTPase binding	RILP;PIFO;RGP1;BICD1;MYRIP;TMEM127;AP1G1;GDI1;MYO5B

TMEM127 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TMEM127 here. Most of them are supplied by our site. Hope this information will be useful for your research of TMEM127.

Clauzure, M; Valdivieso, AG; et al. Disruption of Interleukin-1 beta Autocrine Signaling Rescues Complex I Activity and Improves ROS Levels in Immortalized Epithelial Cells with Impaired Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Function. PLOS ONE 9:-(2014).

Delarasse, C; Smith, P; et al. Novel pathogenic epitopes of myelin oligodendrocyte glycoprotein induce experimental autoimmune encephalomyelitis in C57BL/6 mice. IMMUNOLOGY 140:456-464(2013).