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Official Full Name transmembrane protein 43
Background This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC.
Synonyms TMEM43; transmembrane protein 43; DKFZp586G1919; LUMA; MGC3222; ARVC5; ARVD5
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TMEM43-1117H Recombinant Human TMEM43 Mammalian Cell His
    Human TMEM43-3289H Recombinant Human TMEM43, His-tagged E.coli His
    Human TMEM43-950HCL Recombinant Human TMEM43 293 Cell Lysate HEK293 N/A
    Mouse TMEM43-17045M Recombinant Mouse TMEM43 Protein Mammalian Cell His
    Rat TMEM43-6170R Recombinant Rat TMEM43 Protein Mammalian Cell His
    Zebrafish TMEM43-12440Z Recombinant Zebrafish TMEM43 Mammalian Cell His

    tmem43 involved in several pathways and played different roles in them. We selected most pathways tmem43 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with tmem43 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    tmem43 has several biochemical functions, for example, protein binding, protein self-association. Some of the functions are cooperated with other proteins, some of the functions could acted by tmem43 itself. We selected most functions tmem43 had, and list some proteins which have the same functions with tmem43. You can find most of the proteins on our site.

    Function Related Protein
    protein binding CYHR1; POLD1; CNIH4; NRL; BAG3; STAP1; TPI1; KIFAP3; DNAJB4; MB21D2
    protein self-association ADAM8; SYP; PROSAPIP1; TTN; TP53; DYRK1A; TRIM32; AXIN1; TMEM190; NKX3

    tmem43 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with tmem43 here. Most of them are supplied by our site. Hope this information will be useful for your research of tmem43.

    SIAH1; FDFT1; Ktn1; env; CFTR; Rab5c; Bmpr1a; RAB7A; RAB11A; Tmem109; Tnpo1; MMGT1; C1qbp; VAPA; Tmed2; GOLT1B

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