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TNK1

  • Official Full Name

    tyrosine kinase, non-receptor, 1

  • Overview

    Tyrosine kinase non-receptor 1 (TNK1) is related to the Ack1 (TNK2) non-receptor kinase that binds cdc42 and inhibits GTPase activity of this cell cycle regulator. TNK1 is broadly expressed in embryogenic tissues and leukemia cell lines, but is restricted
  • Synonyms

    TNK1; tyrosine kinase, non-receptor, 1; non-receptor tyrosine-protein kinase TNK1; CD38 negative kinase 1; MGC46193;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TNK1-3326H Recombinant Human TNK1, His-tagged E.coli His 1-377aa
Human TNK1-701H Recombinant Human Tyrosine Kinase, Non-receptor, 1, GST-tagged Insect Cell GST
Human TNK1-886HCL Recombinant Human TNK1 293 Cell Lysate HEK293 N/A
Human TNK1-702H Active Recombinant Human TNK1 Protein (1-510aa), N-GST tagged Sf9 insect cells N-GST
Human TNK1-11H Recombinant Human TNK1 Protein (Full Length), N-His tagged E.coli N-His Full Length
  • Involved Pathway
  • Protein Function
  • Interacting Protein

TNK1 involved in several pathways and played different roles in them. We selected most pathways TNK1 participated on our site, such as Focal Adhesion, which may be useful for your reference. Also, other proteins which involved in the same pathway with TNK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Focal AdhesionSOS1;VTN;ROCK2A;SEPP1;PPP1CA;STYK1;KDRL;MYLK4;ITGA5

TNK1 has several biochemical functions, for example, ATP binding, hormone receptor binding, non-membrane spanning protein tyrosine kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TNK1 itself. We selected most functions TNK1 had, and list some proteins which have the same functions with TNK1. You can find most of the proteins on our site.

Function Related Protein
ATP bindingMAP3K12;FANCM;ATP2B3A;VSIG8B;DDX28;NTRK3A;MAP2K4B;EPHA2A;AARSD1
hormone receptor bindingTNK1;JAK3;TNK2;JAK2B;JAK2A;SRC;TNK2B
non-membrane spanning protein tyrosine kinase activityFGR;SRMS;CLK1;CSK;TNK2B;ABL2;FYNA;ITK;PKDCC
protein bindingSTK24;FRMD4B;HSPE1;AURKAIP1;FARSA;COPS7B;PAEP;PTPRB;C20orf20
protein tyrosine kinase activityAatk;PTK7A;INSRB;MAP2K3;FGFR2;BAZ1B;PTK2;MUSK;TTK
signal transducer activityCXCR2;VMN1R45;GMFB;GNRHR3;ZDHHC13;MTNR1BB;TAS2R116;MRGPRH;PTK2

TNK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TNK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TNK1.

SFN; b4dyc6_human; xmd8-92; biotin_acyl-p_probe; HSP90AB1; CDC37; pi3p; czc8004; linkable pd173955 analogue; linkable vandetanib analogue; linkable sunitinib analogue; linkable staurosporine analogue; linkable imatinib analogue; bosutinib; bisindolylmaleimide iii; imatinib

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