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Official Full Name tripartite motif containing 17
Background The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. The protein is expressed almost exclusively in the testis, but its function is unknown. Multiple alternatively spliced transcript variants have been found for this gene.
Synonyms TRIM17; tripartite motif containing 17; RNF16, tripartite motif containing 17; E3 ubiquitin-protein ligase TRIM17; RBCC; ring finger protein 16; RING finger protein terf; terf; testis RING finger protein; RNF16; TRIM 17; Tripartite motif protein 17; tripartite motif-containing 17; tripartite motif-containing protein 17
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TRIM17-1823HCL Recombinant Human TRIM17 cell lysate N/A
    Mouse TRIM17-17345M Recombinant Mouse TRIM17 Protein Mammalian Cell His
    Rat TRIM17-6271R Recombinant Rat TRIM17 Protein Mammalian Cell His

    trim17 involved in several pathways and played different roles in them. We selected most pathways trim17 participated on our site, such as Cytokine Signaling in Immune system, Immune System, Interferon Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with trim17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine Signaling in Immune system SPTBN1; TRIM6; EIF4E; LAMTOR2; IRF9; NUP50; IFIT2; FRS2A; GBP4; TRIM31
    Immune System LILRB2; FBXO17; FCGR1B; TRAF7; TAX1BP1B; RNF216; MKRN1; DDX41; ASB17; MAP3K8
    Interferon Signaling IFIT11; EIF4E3; TRIM45; IFI35; GBP6; TRIM5; SAMHD1; TRIM48; BST2; EIF4G2A
    Interferon gamma signaling TRIM46; TRIM31; GBP6; TRIM29; GBP2; FCGR1B; TRIM62; OASL; TRIM22; IFI30

    trim17 has several biochemical functions, for example, ligase activity, protein binding, protein binding, bridging. Some of the functions are cooperated with other proteins, some of the functions could acted by trim17 itself. We selected most functions trim17 had, and list some proteins which have the same functions with trim17. You can find most of the proteins on our site.

    Function Related Protein
    ligase activity TRIM8; MARCH4; TRIM62; ACSF2; UBR5; UBR3; TRIM28; LNX1; UBE3B; RING1
    protein binding ATF1; USP20; KLF10; FANCG; CYSLTR2; KCTD13; PAWR; CSDC2; UBASH3A; SWAP70
    protein binding, bridging SPRR1B; SLC9A1; SH2D1B; ADAP2; TCAP; PPP4R2; STX1A; SYNM; ST13; FLRT1
    ubiquitin-protein transferase activity HECW2; CBLB; UBE2E1; TRIM28; UBR5; RNF141; FBXL7; TRIM2; RNF139; MUL1A
    zinc ion binding MORC3A; UBR4; PHF20B; RPS29; ZDHHC22; SERPINB1A; TRIM31; NR2F6A; ABLIM1A; LIMCH1B

    trim17 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with trim17 here. Most of them are supplied by our site. Hope this information will be useful for your research of trim17.

    TRIM39; b4dyc6_human; HSP90AB1; MLF1; q53fc7_human; HSP90AB1; NUDCD3; q96be0_human; AARSD1; CACYBP; NUDC; UBE2D1; MNAT1; UBE2D3; UBE2H

    Kao, TH; Liao, HF; et al. Ectopic DNMT3L Triggers Assembly of a Repressive Complex for Retroviral Silencing in Somatic Cells. JOURNAL OF VIROLOGY 88:10680-10695(2014).
    Smith, S; Gabhann, JN; et al. Estrogen Receptor alpha Regulates Tripartite Motif-Containing Protein 21 Expression, Contributing to Dysregulated Cytokine Production in Systemic Lupus Erythematosus. ARTHRITIS & RHEUMATOLOGY 66:163-172(2014).

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