|Official Full Name||Tripartite Motif Containing 27|
|Background||This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a;RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nuclear matrix. It;interacts with the enhancer of polycomb protein and represses gene transcription. It is also thought to be involved in;the differentiation of male germ cells. Fusion of the N-terminus of this protein with the truncated C-terminus of the;RET gene product has been shown to result in production of the ret transforming protein.|
|Synonyms||TRIM27; tripartite motif containing 27; RFP; RNF76; zinc finger protein RFP; OTTHUMP00000029314; OTTHUMP00000107284; ret finger protein; RING finger protein 76; RFP transforming protein; tripartite motif-containing 27; tripartite motif protein TRIM27; tripartite motif-containing protein 27|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
trim27 involved in several pathways and played different roles in them. We selected most pathways trim27 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with trim27 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
trim27 has several biochemical functions, for example, DNA binding, ligase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by trim27 itself. We selected most functions trim27 had, and list some proteins which have the same functions with trim27. You can find most of the proteins on our site.
|DNA binding||CHD2; ZFP580; TFB1M; BLZF1; ZNF518A; ZFP451; HIST1H2BG; ZBTB5; HIST1H3A; ZKSCAN6|
|ligase activity||PPIL2; UBE3B; PJA1; PIAS3; CBLC; ZSWIM2; RNF38; TRIP12; UFL1; RTCD1|
|metal ion binding||FOXP3; ZNF559-ZNF177; ZNF225; ZDHHC3A; SMYD1B; PRSS1; TIMM8A2; ZFP367; ZNF484; ITGA1|
|nucleic acid binding||GFI1AB; ZBTB10; ZBTB7C; SFRS3B; ZFP35; ENDOG; ZEB2B; RNASE13; SP5L; SALL3|
|protein binding||CEP68; HMGA2; IL6; CSRP2BP; RSL24D1; OXA1L; PSMD5; SLC30A1; OAS1; ALOX12B|
|transmembrane receptor protein tyrosine kinase activity||ERBB3A; DDR1; KIT; FLT3; EPHB2B; NTRK3; EPHB4; FLT4; KITA; EK1|
|ubiquitin-protein transferase activity||TRAF4B; FBXO2; SHPRH; BIRC8; UBE2B; TTC3; CMTM2A; TRIM68; RCHY1; RNF151|
|zinc ion binding||ADAMTS15A; DTX1; NEURL1AB; RNF19A; TRIML1; NR1H2; CA5A; HERC2; PRICKLE1B; SIAH2L|
trim27 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with trim27 here. Most of them are supplied by our site. Hope this information will be useful for your research of trim27.
NEDD9; JOSD1; PPP1R18; ZNF417; TUFT1