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Official Full Name tripartite motif containing 41
Background This gene encodes a member of the tripartite motif (TRIM) family. The TRIM family is characterized by a signature motif composed of a RING finger, one or more B-box domains, and a coiled-coil region. This encoded protein may play a role in protein kinase C signaling. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms TRIM41; tripartite motif containing 41; E3 ubiquitin-protein ligase TRIM41; MGC1127; RINCK; RING finger protein that interacts with C kinase; RING finger-interacting protein with C kinase; RING-finger protein that interacts with C kinase; MGC31991
    • Species :
    • Chicken
    • Human
    • Mouse
    • Source :
    • E.coli
    • Mammalian Cell
    • Tag :
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TRIM41-447H Recombinant Human TRIM41 Protein, His-tagged E.coli His
    Mouse TRIM41-17370M Recombinant Mouse TRIM41 Protein Mammalian Cell His
    Chicken TRIM41-2376C Recombinant Chicken TRIM41 Mammalian Cell His

    trim41 involved in several pathways and played different roles in them. We selected most pathways trim41 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &amp, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with trim41 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System DCTN6; PJA2; UBR2; CDKN1A; PIK3AP1; TRIM69; BTLA; RNF182; KLRB1B; TRAF7
    Antigen processing: Ubiquitination &amp RBCK1; DTX3L; UBE2E3; VPRBP; LTN1; ASB2; HECTD3; RNF123; SPSB2; WWP1
    Proteasome degradation RNF182; ASB11; FBXO27; UFL1; MKRN1; RNF41; ASB18; TRIM50; UBE2V1; VPRBP
    Class I MHC mediated antigen processing &amp MKRN1; KLHL20; SEC61B; SPSB2; PJA2; UBE2E3; RBCK1; ASB13; LRRC41; RNF6
    presentation DTX3L; ASB14; RNF138; RNF4; SEC61B; HUWE1; UBE2E3; CTSL2; PJA2; ASB18
    Immune System TRIM5; WSB1; CD226; ASB4; SIGLEC11; AF251705; TLR6; KIF5B; ART1; MICA

    trim41 has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity, coenzyme F420-0 gamma-glutamyl ligase activity, coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by trim41 itself. We selected most functions trim41 had, and list some proteins which have the same functions with trim41. You can find most of the proteins on our site.

    Function Related Protein
    UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity ARIH1L; HECW2; TMEM129; NEURL1B; ZNRF3; MARCH11; TRIM41; DTX1; RNF169; MARCH4
    coenzyme F420-0 gamma-glutamyl ligase activity UBE2IA; RNF187; NEURL1B; TRIM71; MARCH11; RNF144AB; SIAH1A; DTX1; RFWD2; SHRPRBCK1R
    coenzyme F420-2 alpha-glutamyl ligase activity ITCHA; DTX1; RNF149; TRIM71; UBE2IB; HERC2; RNF144AB; TMEM129; UBR1; TRIM41
    ligase activity RFWD3; TRIM5; HERC4; CDC34B; RNF114; RNF115; SMURF1; UBE2G1B; RNF34; MID2
    metal ion binding STK24; UGP2; PPARAA; CYP2C38; ZFP513; ZFP93; ZFP488; INSM1B; CUBN; CA
    protein binding SIP1; NR0B2; HM13; SNX27; STX11; MYO7B; GSK3A; PRDX6; SLC16A3; HIST1H2AH
    protein-glutamic acid ligase activity MARCH6; MARCH9; RAG1; MGRN1A; ARIH1L; MUL1A; MARCH5L; TRIM71; RNF180; ITCHA
    protein-glycine ligase activity SIAH2L; ZNRF2B; TTLL3; UBR1; TRIM50; MYLIPB; TRIM71; ITCHA; DTX1; MYLIPA
    protein-glycine ligase activity, elongating LTN1; TRIM71; DTX1; MARCH5L; MGRN1A; UBE2IB; MYLIPB; RNF144AB; MARCH11; SIAH2L
    protein-glycine ligase activity, initiating HECW2; RNF144AA; SIAH2L; RNF149; RC3H2; HERC2; RNF169; MARCH9; MGRN1A; MARCH4
    ribosomal S6-glutamic acid ligase activity RFWD2; G2E3; TRIM71; TRIM41; MGRN1A; SIAH1A; RC3H2; RNF149; HERC2; TMEM129
    tubulin-glutamic acid ligase activity SIAH2L; RNF187; UBE2IB; UBE2IA; HECW2; RNF180; TMEM129; SIAH1A; MARCH4; MARCH9
    tubulin-glycine ligase activity UBR1; RNF187; MYLIPA; RNF149; MARCH5L; TMEM129; ITCHA; ARIH1L; LTN1; TRIM50
    zinc ion binding MECR; ZNF84; PHC2; TRAF4; ZDHHC21; MARCH10; UQCRC2B; QPCT; PHC1; CAR1

    trim41 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with trim41 here. Most of them are supplied by our site. Hope this information will be useful for your research of trim41.


    Cui, J; Chen, YJ; et al. Mechanisms and pathways of innate immune activation and regulation in health and cancer. HUMAN VACCINES & IMMUNOTHERAPEUTICS 10:3270-3285(2014).
    Hering, DM; Olenski, K; et al. Genome-wide association study for poor sperm motility in Holstein-Friesian bulls. ANIMAL REPRODUCTION SCIENCE 146:89-97(2014).

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