TRIM41

  • Official Full Name

    tripartite motif containing 41
  • Overview

    This gene encodes a member of the tripartite motif (TRIM) family. The TRIM family is characterized by a signature motif composed of a RING finger, one or more B-box domains, and a coiled-coil region. This encoded protein may play a role in protein kinase C signaling. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    TRIM41;tripartite motif containing 41;E3 ubiquitin-protein ligase TRIM41;MGC1127;RINCK;RING finger protein that interacts with C kinase;RING finger-interacting protein with C kinase;RING-finger protein that interacts with C kinase;MGC31991
Cat.# Product name Source (Host) Species Tag Protein Length Price
TRIM41-17370M Recombinant Mouse TRIM41 Protein Mammalian Cells Mouse His
TRIM41-2376C Recombinant Chicken TRIM41 Mammalian Cells Chicken His
TRIM41-447H Recombinant Human TRIM41 Protein, His-tagged E.coli Human His
TRIM41-9606M Recombinant Mouse TRIM41 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
TRIM41-9606M-B Recombinant Mouse TRIM41 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    TRIM41 involved in several pathways and played different roles in them. We selected most pathways TRIM41 participated on our site, such as Adaptive Immune System,Antigen processing: Ubiquitination &amp,Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM41 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Antigen processing: Ubiquitination &amp RNF138,UBE2J2,KLHL20,UBR1,UBA5,HECTD3,LRSAM1,ASB17,LRR1,TRIM9
    Adaptive Immune System TRIM39,FBXO44,FBXO27,ASB6,TREML4,LAIR2,LILRA3,CTS7,CYBB,TREML1
    presentation HUWE1,LRR1,UBE2V1,DZIP3,CTSL2,ERAP2,UBA5,ERAP1,UBE2V2,UBE2U
    Immune System BTR02,NLRP4B,IRF4,MYO9B,TRIM29,CTLA4,UBE2F,LTN1,RCA2.1,Siglece
    Proteasome degradation UBE2F,DTX3L,ASB3,STUB1,RNF144B,UBE2J2,BLMH,ASB9,ASB8,SPSB2
    Class I MHC mediated antigen processing &amp FBXO44,RNF19B,CTSL2,ASB10,CYBB,KLHL21,ASB7,UBE2U,ERAP1,B2ML

    Protein Function

    TRIM41 has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity,coenzyme F420-0 gamma-glutamyl ligase activity,coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM41 itself. We selected most functions TRIM41 had, and list some proteins which have the same functions with TRIM41. You can find most of the proteins on our site.

    Function Related Protein
    metal ion binding TRIM35,GALNT9,CYP19A1A,ASXL3,ZNF277,ZNF582,ZBTB4,PDZRN3B,PFKM,ZFP36
    tubulin-glutamic acid ligase activity ITCHA,G2E3,TRIM71,MYLIPA,MARCH5L,RNF180,RNF144AB,SIAH1A,MYLIPB,UBE2IB
    ribosomal S6-glutamic acid ligase activity ZNRF3,MARCH11,MYLIPB,RNF180,UBE2M,RNF144AA,TMEM129,NEURL1B,RC3H2,UBR1
    protein binding GSE1,TLDC2,TRIM27,GTPBP10,HOXC4,JAM3,TNFRSF10B,RBPJ,F12,RBX1
    ligase activity TRAF3,TRIM4,MGRN1,TOPORS,TRIM8,BRCA1,TRIM37,NEURL3,UCHL1,RNF168
    protein-glycine ligase activity, initiating DTX1,LTN1,RAG1,MARCH11,SIAH1A,HERC2,RNF144AA,MARCH4,SIAH2L,RNF187
    coenzyme F420-2 alpha-glutamyl ligase activity MGRN1A,MARCH6,RC3H2,ZNRF2B,UBR1,RNF187,NEURL3,MYLIPB,UBE2IB,RNF180
    coenzyme F420-0 gamma-glutamyl ligase activity ZNRF2B,SHRPRBCK1R,LTN1,MYLIPA,ARIH1L,TMEM129,MARCH9,RNF144AA,DTX1,RNF169
    protein-glycine ligase activity, elongating RNF149,ARIH1L,SIAH2L,MARCH4,ZNRF3,MYLIPB,MARCH6,MGRN1A,RNF144AA,RC3H2

    Interacting Protein

    TRIM41 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM41 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM41.

    Rpgrip1l

    Resources

    References

    • Cui, J; Chen, YJ; et al. Mechanisms and pathways of innate immune activation and regulation in health and cancer. HUMAN VACCINES & IMMUNOTHERAPEUTICS 10:3270-3285(2014).
    • Hering, DM; Olenski, K; et al. Genome-wide association study for poor sperm motility in Holstein-Friesian bulls. ANIMAL REPRODUCTION SCIENCE 146:89-97(2014).

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