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Official Full Name tripartite motif containing 41
Background This gene encodes a member of the tripartite motif (TRIM) family. The TRIM family is characterized by a signature motif composed of a RING finger, one or more B-box domains, and a coiled-coil region. This encoded protein may play a role in protein kinase C signaling. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms TRIM41; tripartite motif containing 41; E3 ubiquitin-protein ligase TRIM41; MGC1127; RINCK; RING finger protein that interacts with C kinase; RING finger-interacting protein with C kinase; RING-finger protein that interacts with C kinase; MGC31991
    • Species :
    • Chicken
    • Human
    • Mouse
    • Source :
    • E.coli
    • Mammalian Cell
    • Tag :
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TRIM41-447H Recombinant Human TRIM41 Protein, His-tagged E.coli His
    Mouse TRIM41-17370M Recombinant Mouse TRIM41 Protein Mammalian Cell His
    Chicken TRIM41-2376C Recombinant Chicken TRIM41 Mammalian Cell His

    trim41 involved in several pathways and played different roles in them. We selected most pathways trim41 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &amp, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with trim41 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System FAM49BA; TRAT1; FGF18B; ASB2; ASB3; LAIR1; DYNLL2; UBE2L6; CD200R2; KLRB1B
    Antigen processing: Ubiquitination &amp RNF6; CMTM2A; TRIM63; UBE2E3; RNF14; RNF138; ASB13; UFL1; UBE2U; RNF25
    Proteasome degradation UBR1; UBE2J2; TRIM50; WSB1; UFL1; RNF123; UBE2L6; TRIM11; UBE2V1; VPRBP
    Class I MHC mediated antigen processing &amp UBE2V1; ASB2; TRIM63; TRIM9; ASB9; LRRC41; RNF144B; UBE2F; ASB7; CD207
    presentation RNF123; UBE2L6; WWP1; RBCK1; FBXO17; ASB3; ASB11; FBXO44; UBA5; TRIM9
    Immune System SOCS3A; CLEC4D; FCN2; MAP3K8; ASB18; AMICA1; CLEC2G; TRIM17; ASB8; IFIT14

    trim41 has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity, coenzyme F420-0 gamma-glutamyl ligase activity, coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by trim41 itself. We selected most functions trim41 had, and list some proteins which have the same functions with trim41. You can find most of the proteins on our site.

    Function Related Protein
    UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity RNF187; NEURL1B; MARCH5L; TRIM41; TRIM71; RNF169; SIAH2L; RNF144AB; G2E3; UBE2IB
    coenzyme F420-0 gamma-glutamyl ligase activity RNF180; NEURL3; UBR1; RC3H2; RNF187; TRIM71; NEURL1B; MARCH6; RFWD2; ARIH1L
    coenzyme F420-2 alpha-glutamyl ligase activity MYLIPB; UBR1; SIAH2L; SIAH1A; TRIM50; HERC2; RAG1; DTX1; RNF187; LTN1
    ligase activity UBE2L3A; RNF4; MARCH6; TRIM32; G2E3; E4F1; TRIM62; ACSM2; BRCA1; LIPT2
    metal ion binding PPM1DA; LDB3A; SLX1B; CLCA4; SH3RF3; ITGAL; ZNF443; ZNF410; ZNF740B; KLF11B
    protein binding UBE2U; RINT1; IKZF3; FBXO4; TAOK1; ERO1L; UBE2M; RGS20; HSFX1; NXF1
    protein-glutamic acid ligase activity RC3H2; ARIH1L; TRIM50; ITCHA; MARCH6; RNF144AB; NEURL3; TMEM129; RNF149; RAG1
    protein-glycine ligase activity MARCH9; DTX1; RAG1; ZNRF2B; HERC2; SHRPRBCK1R; TRIM71; G2E3; MARCH4; MARCH5L
    protein-glycine ligase activity, elongating ARIH1L; RNF149; TRIM50; TMEM129; HECW2; TRIM41; SIAH1A; MARCH6; MARCH5L; RNF169
    protein-glycine ligase activity, initiating RNF144AB; RFWD2; SIAH2L; NEURL3; RNF169; RNF149; UBE2IB; NEURL1B; MUL1A; TRIM50
    ribosomal S6-glutamic acid ligase activity HERC2; UBE2M; DTX1; RFWD2; LTN1; ARIH1L; G2E3; RAG1; ZNRF2B; UBE2IB
    tubulin-glutamic acid ligase activity RFWD2; SIAH1A; MARCH5L; TRIM41; ITCHA; HERC2; RAG1; UBE2IA; TRIM71; ARIH1L
    tubulin-glycine ligase activity NEURL3; ZNRF3; ARIH1L; MYLIPB; MARCH6; LTN1; SHRPRBCK1R; ITCHA; MARCH5L; TRIM71
    zinc ion binding SCEL; KAT7A; NSMCE1; PHF8; CRYZ; TRIM43C; NR4A1; ZRANB1B; TAB2; Npepo

    trim41 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with trim41 here. Most of them are supplied by our site. Hope this information will be useful for your research of trim41.


    Cui, J; Chen, YJ; et al. Mechanisms and pathways of innate immune activation and regulation in health and cancer. HUMAN VACCINES & IMMUNOTHERAPEUTICS 10:3270-3285(2014).
    Hering, DM; Olenski, K; et al. Genome-wide association study for poor sperm motility in Holstein-Friesian bulls. ANIMAL REPRODUCTION SCIENCE 146:89-97(2014).

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