TRIM41
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Official Full Name
tripartite motif containing 41 -
Overview
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM family is characterized by a signature motif composed of a RING finger, one or more B-box domains, and a coiled-coil region. This encoded protein may play a role in protein kinase C signaling. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
TRIM41;tripartite motif containing 41;E3 ubiquitin-protein ligase TRIM41;MGC1127;RINCK;RING finger protein that interacts with C kinase;RING finger-interacting protein with C kinase;RING-finger protein that interacts with C kinase;MGC31991
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TRIM41-17370M | Recombinant Mouse TRIM41 Protein | Mammalian Cells | Mouse | His |
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| TRIM41-2376C | Recombinant Chicken TRIM41 | Mammalian Cells | Chicken | His |
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| TRIM41-447H | Recombinant Human TRIM41 Protein, His-tagged | E.coli | Human | His |
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| TRIM41-9606M | Recombinant Mouse TRIM41 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| TRIM41-9606M-B | Recombinant Mouse TRIM41 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
TRIM41 involved in several pathways and played different roles in them. We selected most pathways TRIM41 participated on our site, such as Adaptive Immune System,Antigen processing: Ubiquitination &,Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM41 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Adaptive Immune System | DYNC1H1,LILRB2,HCST,RAP1GAP2B,KIF22,AP1M2,UBE2V1,NRG2A,NRG3,DNM1 |
| presentation | SH3RF1,ASB17,WSB1,UBE2U,ASB18,ERAP1,DTX3L,TRIM9,FBXO27,LRSAM1 |
| Antigen processing: Ubiquitination & | UBE2L6,NPEPPS,ASB3,RNF138,ASB18,ATG7,UBR2,ASB11,WSB1,FBXO27 |
| Immune System | RAPGEF3,DEFB1,SEC61B,BFB,KPNA5,KIF5B,SPSB4,KIF2B,CR1,DEFA1 |
| Proteasome degradation | SPSB2,BLMH,CMTM2A,PJA2,UBA5,PJA1,UBE2U,ASB2,LRSAM1,UBE2L6 |
| Class I MHC mediated antigen processing & | LTN1,ARIH2,ASB4,SEC23A,TRAF7,FBXO44,SPSB4,RNF182,RNF25,SEC24A |
Protein Function
TRIM41 has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity,coenzyme F420-0 gamma-glutamyl ligase activity,coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM41 itself. We selected most functions TRIM41 had, and list some proteins which have the same functions with TRIM41. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| coenzyme F420-0 gamma-glutamyl ligase activity | RNF149,MARCH11,RFWD2,NEURL3,MARCH4,NEURL1B,LTN1,MGRN1A,SHRPRBCK1R,TRIM50 |
| ligase activity | PDZRN3,GLULB,RLIM,CPS1,MARCH3,NEDD4L,UBR2,DTX3,RBX1,BRAP |
| zinc ion binding | ZNF75D,TRIM68,RNF31,ZGLP1,DMD,RARGA,Npepo,DNMT1,GATA2A,ZDHHC5 |
| coenzyme F420-2 alpha-glutamyl ligase activity | UBE2IB,LTN1,RNF144AA,MARCH5L,SIAH2L,MARCH6,SIAH1A,MUL1A,ZNRF2B,RNF187 |
| protein-glycine ligase activity, elongating | TMEM129,MGRN1A,ZNRF2B,MARCH11,ITCHA,SIAH2L,RNF144AB,RNF169,MYLIPB,NEURL3 |
| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity | HECW2,MARCH9,RNF149,UBE2IA,TRIM71,RAG1,MYLIPB,RNF187,TMEM129,G2E3 |
| protein-glycine ligase activity | TRIM71,MGRN1A,RNF180,NEURL3,HERC2,UBE2IB,TTLL3,ARIH1L,SIAH1A,ITCHA |
| tubulin-glutamic acid ligase activity | NEURL3,SIAH2L,MGRN1A,RNF149,RNF180,MUL1A,TTLL1,RFWD2,MARCH6,HERC2 |
| tubulin-glycine ligase activity | ZNRF2B,MARCH9,RNF187,UBE2IA,RFWD2,MARCH6,FLR,MARCH5L,SIAH2L,TRIM50 |
Interacting Protein
TRIM41 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM41 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM41.
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References
- Cui, J; Chen, YJ; et al. Mechanisms and pathways of innate immune activation and regulation in health and cancer. HUMAN VACCINES & IMMUNOTHERAPEUTICS 10:3270-3285(2014).
- Hering, DM; Olenski, K; et al. Genome-wide association study for poor sperm motility in Holstein-Friesian bulls. ANIMAL REPRODUCTION SCIENCE 146:89-97(2014).
