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Official Full Name tripartite motif containing 6
Background The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, B-box type 1 and B-box type 2 domain, and a coiled-coil region. The protein localizes to the nucleus, but its specific function has not been identified. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. Alternative splicing results in multiple transcript variants. A read-through transcript from this gene into the downstream TRIM34 gene has also been observed, which results in a fusion product from these neighboring family members.
Synonyms TRIM6; tripartite motif containing 6; tripartite motif-containing protein 6; RNF89; Ring Finger Protein 89; TRIM 6; Tripartite motif containing protein 6; tripartite motif-containing 6
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TRIM6-3415H Recombinant Human TRIM6, GST-tagged E.coli GST
    Human TRIM6-3918H Recombinant Human TRIM6 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human TRIM6-765HCL Recombinant Human TRIM6 293 Cell Lysate HEK293 N/A
    Mouse TRIM6-17386M Recombinant Mouse TRIM6 Protein Mammalian Cell His
    Mouse Trim6-6661M Recombinant Mouse Trim6 Protein, Myc/DDK-tagged HEK293T Myc/DDK

    trim6 involved in several pathways and played different roles in them. We selected most pathways trim6 participated on our site, such as Cytokine Signaling in Immune system, Immune System, Interferon Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with trim6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine Signaling in Immune system TRIM5; TAB1; CNKSR1; LGALS9; EIF4E; FRS2; TRIM6; MARK3; FGF18B; ISG20
    Immune System EIF4E3; ABI1A; KLHL21; STIM1B; NLRP3; CD300LG; POLR3GLA; CTSB; BTR16; STUB1
    Interferon Signaling TRIM68; HLA-DQB2; GBP5; IRF6; ISG20; IFITM2; IRF2; TRIM2; TRIM38; TRIM14
    Interferon gamma signaling TRIM5; TRIM46; TRIM3; GBP2; GBP4; IRF6; TRIM38; TRIM26; FCGR1B; GBP1

    trim6 has several biochemical functions, for example, ligase activity, molecular_function, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by trim6 itself. We selected most functions trim6 had, and list some proteins which have the same functions with trim6. You can find most of the proteins on our site.

    Function Related Protein
    ligase activity ITCH; MIB2; MIB1; RNF146; RFFL; CBLC; LTN1; UBR7; BIRC2; RNF125
    molecular_function GVIN1; H2AFV; ANKRD10B; SAMT1; CBLN9; RCCD1; ARMC5; GPKOW; DEFB7; LPIN1
    protein binding RCOR1; TSSK4; GLA; CCDC141; DDX23; C5orf20; ALDOA; EIF3H; VPS41; SEPT2
    protein binding, bridging TNNT2A; FSCN2; FLRT3; PPP2R3A; FGG; LOR; FGB; FLRT2; MMS19; RBM14
    protein kinase binding ADCY6; VRK2; HSPB1; KIF13B; CALM3; CRY1; IRS2; ERRFI1; PTEN; SLC12A5
    protein tyrosine kinase binding TRIM6
    transcription factor binding FIGLA; FOXC1; SORBS3; FHL2; DIP2C; DDX3X; KEAP1; PARD6A; PPP1R13BB; E2F1
    ubiquitin protein ligase activity NHLRC1; SIAH2L; RNF19A; LRSAM1; MED31; CDC34B; RNF144B; UBE2KA; UBE3A; RABGEF1
    zinc ion binding SREK1IP1; CA2; BIRC2; MEP1A.2; LHX4; ZNF212; C6AST4; MEX3B; LHX2; SRSF7B

    trim6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with trim6 here. Most of them are supplied by our site. Hope this information will be useful for your research of trim6.

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