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TRIT1

  • Official Full Name

    tRNA isopentenyltransferase 1

  • Overview

    tRNA isopentenyltransferase, mitochondrial is an enzyme that in humans is encoded by the TRIT1 gene. It catalyzes the addition of an isopentenyl group from dimethylallyl diphosphate (DMAPP) onto adenosine residue 37 of certain tRNA molecules.
  • Synonyms

    TRIT1; tRNA isopentenyltransferase 1; tRNA dimethylallyltransferase, mitochondrial; FLJ20061; IPT; 2310075G14Rik; AI314635; AV099619; MGC149242; MGC149243; mitochondrial; MOD5; AI314189; hGRO1; IPP transferase; IPPT; IPTase; Isopentenyl diphosphate:tRNA isopentenyltransferase; Isopentenyl-diphosphate:tRNA isopentenyltransferase; MOD5_HUMAN; OTTMUSP00000009314; Putative protein TR2IT1; RP23-121J14.6; TRIT 1; tRNA dimethylallyltransferase; tRNA isopentenylpyrophosphate transferase; tRNA isopentenyltransferase; tRNA isopentenyltransferase mitochondrial;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TRIT1-31617TH Recombinant Human TRIT1, His-tagged E.coli His
Human TRIT1-1839HCL Recombinant Human TRIT1 cell lysate N/A
Human TRIT1-2811H Recombinant Human TRIT1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Mouse TRIT1-17412M Recombinant Mouse TRIT1 Protein Mammalian Cell His
Mouse TRIT1-9633M-B Recombinant Mouse TRIT1 Protein Pre-coupled Magnetic Beads HEK293
Mouse TRIT1-9633M Recombinant Mouse TRIT1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish TRIT1-3919Z Recombinant Zebrafish TRIT1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • TRIT1 Related Articles

TRIT1 involved in several pathways and played different roles in them. We selected most pathways TRIT1 participated on our site, such as Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Metabolic pathwaysST3GAL5;G6PCA.2;POLR3GLB;CYCS;MTAP;BTD;HADHAB;PDHA1B;AMPD2

TRIT1 has several biochemical functions, for example, ATP binding, metal ion binding, tRNA dimethylallyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIT1 itself. We selected most functions TRIT1 had, and list some proteins which have the same functions with TRIT1. You can find most of the proteins on our site.

Function Related Protein
ATP bindingULK1;SGK2B;ABCG2A;PFKL;ACACB;CPS1;DDX54;PRKCQ;PRKG1
metal ion bindingZFP689;ACVRL1;ZFPL1;CHSY3;PM20D1.1;MICAL2;RPP21;DDX11;SALL1
tRNA dimethylallyltransferase activity

TRIT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIT1.

C8orf30A; SMYD3

Lindner, AC; Lang, D; et al. Isopentenyltransferase-1 (IPT1) knockout in Physcomitrella together with phylogenetic analyses of IPTs provide insights into evolution of plant cytokinin biosynthesis. JOURNAL OF EXPERIMENTAL BOTANY 65:2533-2543(2014).
Lamichhane, TN; Mattijssen, S; et al. Human Cells Have a Limited Set of tRNA Anticodon Loop Substrates of the tRNA Isopentenyltransferase TRIT1 Tumor Suppressor. MOLECULAR AND CELLULAR BIOLOGY 33:4900-4908(2013).
  • Q&As
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