TRPC2
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Official Full Name
transient receptor potential cation channel, subfamily C, member 2 -
Overview
may mediate vomeronasal sensory transduction; may play a role in pheromone signaling cascade -
Synonyms
TRPC2;transient receptor potential cation channel, subfamily C, member 2;short transient receptor potential channel 2;Trp2;Trrp2;rTRP2;Short transient receptor potential channel;Transient receptor protein 2;TRP-2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TRPC2-2811H | Recombinant Human TRPC2 protein, His-tagged | E. coli | Human | His | ||
| TRPC2-17444M | Recombinant Mouse TRPC2 Protein | Mammalian Cells | Mouse | His |
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| RFL15808BF | Recombinant Full Length Bovine Short Transient Receptor Potential Channel 2 Homolog(Trpc2) Protein, His-Tagged | E.coli | Bovine | His | Full L. Full Length (1-432) |
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| TRPC2-1158HFL | Recombinant Human TRPC2 protein, His&Flag-tagged | HEK293 | Human | Flag&His | Full L. |
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| TRPC2-9654M | Recombinant Mouse TRPC2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| TRPC2-9654M-B | Recombinant Mouse TRPC2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
TRPC2 involved in several pathways and played different roles in them. We selected most pathways TRPC2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TRPC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
TRPC2 has several biochemical functions, for example, calcium channel activity,calmodulin binding,damaged DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRPC2 itself. We selected most functions TRPC2 had, and list some proteins which have the same functions with TRPC2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| diacylglycerol binding | RASGRP1,RASGRP3,UNC13B,RASGRP4,UNC13C,UNC13A,CDIPT,RASGRP2 |
| store-operated calcium channel activity | ORAI2,TRPC7,ORAI3,ORAI1B,STIM2,TRPC5,ZP3,TRPC1,ORAI1,TRPC5A |
| calcium channel activity | AKR1C1,CACNG8A,UBXN6,GRIN3A,CACNG1A,SLC24A2,GPM6A,CACNA1C,GRIN2A,CATSPER2 |
| ion channel activity | CLCN3,GRIN2A,FXYD7,FXYD6,CACNA1SB,CLCN1A,GRIA3B,CNGA5,KCNC1B,GJD3 |
| protein binding | ADA,TMEM149,RBM15,TXK,FAM83A,HYPK,PSMD14,PPP1R7,CWC22,NCBP2 |
| inositol 1,4,5 trisphosphate binding | TRPC2B,TRPC3,TRPC5,TRPC6A,TRPC1,TRPC5A,AKR1C1,TRPC6,TRPC4,PLCL1 |
| damaged DNA binding | CREBBP,RAD23AA,RAD52,RUVBL2,POLD1,REV1,APTX,RAD23B,XRCC1,RAD1 |
| calmodulin binding | TRPM4,PLCB3,MKNK2,CTH,PHKG1A,MKNK2B,C2orf62,UBR4,MIP,MAPKAPK5 |
Interacting Protein
TRPC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRPC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRPC2.
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References
- Tran, VT; Ho, PT; et al. Mechanotransduction Channels of the Trabecular Meshwork. CURRENT EYE RESEARCH 39:291-303(2014).
- Zhang, P; Yang, C; et al. Urine stimulation activates BK channels in mouse vomeronasal neurons. JOURNAL OF NEUROPHYSIOLOGY 100:1824-1834(2008).
