trpm6 Protein, transient receptor potential cation channel, subfamily M, member 6


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Official Full Name transient receptor potential cation channel, subfamily M, member 6
Background TRPM6 is a transient receptor potential ion channel associated with hypomagnesemia with secondary hypocalcemia.
Synonyms TRPM6; transient receptor potential cation channel, subfamily M, member 6; HOMG, HSH, hypomagnesemia, secondary hypocalcemia; transient receptor potential cation channel subfamily M member 6; CHAK2; FLJ22628; channel kinase 2; melastatin-related TRP cati
    • Species :
    • Human
    • Zebrafish
    • Source :
    • Mammalian Cell
    • Tag :
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TRPM6-824H Recombinant Human TRPM6 Mammalian Cell His
    Zebrafish TRPM6-8098Z Recombinant Zebrafish TRPM6 Mammalian Cell His

    trpm6 involved in several pathways and played different roles in them. We selected most pathways trpm6 participated on our site, such as Ion channel transport, Mineral absorption, Stimuli-sensing channels, which may be useful for your reference. Also, other proteins which involved in the same pathway with trpm6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ion channel transport ANO10A; ATP1A1A.5; ATP2B1B; GSDMA2; PDZD11; CLCN4; WNK1; Ano3; TRPM1A; TRPC4APA
    Mineral absorption SLC5A1; SLC31A1; FXYD2; HEPH; TRPV6; MT2; ATP2B1; MT1G; MT1F; MT1
    Stimuli-sensing channels MCOLN2; CLCA1; TRPC4B; MCOLN3; TRPA1A; TSC22D3; TRPC4A; SGK2; TRPC4APB; ANO6
    Transmembrane transport of small molecules SLC20A1; SLC30A1A; CLIC2; TRPA1A; ATP2C1; ATP8B1; ANO10; AQP10A; SLC5A8; SLC9A10

    trpm6 has several biochemical functions, for example, ATP binding, calcium channel activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by trpm6 itself. We selected most functions trpm6 had, and list some proteins which have the same functions with trpm6. You can find most of the proteins on our site.

    Function Related Protein
    calcium channel activity ORAI1B; GRIN2A; PANX1; AKR1C1; UBXN6; TRPV5; TRPC6A; SLC24A4; TRPV3; GRIN3A
    metal ion binding CYP2K17; MOB2; FAM20B; ZNF560; ZNF436; KDM4D; MT1HL1; ZNF69; NGLY1; VEPH1
    protein binding TMEM64; FAM46A; XRCC5; TH; KHDRBS3; DDB2; HIST1H2BF; RITA1; DHRS2; PLCB1
    protein serine/threonine kinase activity MAP4K2; RIPK1; MAPK12A; ROCK2B; SRPK1A; CAMK2G1; MAP2K5; OBSCN; SBK1; MAP2K1

    trpm6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with trpm6 here. Most of them are supplied by our site. Hope this information will be useful for your research of trpm6.

    MYH9; MYH10; MYH14

    Costa, A; Tejpar, S; et al. Hypomagnesaemia and targeted anti-epidermal growth factor receptor (EGFR) agents. TARGETED ONCOLOGY 6:227-233(2011).
    Dimke, H; van der Wijst, J; et al. Effects of the EGFR Inhibitor Erlotinib on Magnesium Handling. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 21:1309-1316(2010).

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