TTC6
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Official Full Name
tetratricopeptide repeat domain 6 -
Synonyms
TTC6;tetratricopeptide repeat domain 6;C14orf25, chromosome 14 open reading frame 25 , NCRNA00291, non protein coding RNA 291;tetratricopeptide repeat protein 6;C14orf25;MGC119358;MGC119360;hCG_20713;MGC119361;TPR repeat protein 6;NCRNA00291
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TTC6-3475H | Recombinant Human TTC6, His-tagged | E.coli | Human | His | C-353aa |
Involved Pathway
TTC6 involved in several pathways and played different roles in them. We selected most pathways TTC6 participated on our site, such as B Cell Receptor Signaling Pathway,Gene Expression,Herpes simplex infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with TTC6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| B Cell Receptor Signaling Pathway | RASGRP3,NFKBIA,PIK3CB,CR2,SOS1,CDK7,HRAS,CRK,CDK2,NFATC2 |
| Spliceosome | SART1,SRSF1,TRA2B,NHP2L1B,PRPF40B,MAGOH,USP39,SRSF9,SNRNP27,SNRPA1 |
| Herpes simplex infection | SFRS3B,PML,CSNK2A2,EIF2AK2,CASP8,IFIT1,CD74A,OAS2,DAXX,HLA-DRB5 |
| Viral carcinogenesis | EIF2AK2,HIST2H4A,HIST1H2BP,MAD1L1,IKBKG,HIST1H4M,HIST1H2BG,VDAC3,HDAC10,MDM2 |
| MicroRNAs in cancer | GLS,THBS1,CCND2,STMN1,WNT3,MAP2K2,EP300,PLCG2,PIK3R2,MMP16 |
| mRNA Splicing | HNRNPA0L,RBM5,RNPC3,HNRPL,SF3A1,ZCRB1,PTBP1A,SF3A3,SFRS3A,HNRNPD |
| Processing of Capped Intron-Containing Pre-mRNA | CSTF2,CSTF3,SUGP1,PCBP2,RBM5,SF3B4,HNRNPA0L,HNRNPH1L,NXF1,THOC4 |
| Gene Expression | HNRNPA0L,TSNAX,ZNF34,RRAGB,ZNF697,CSTF2,ZNF560,ZNF689,FAM36A,NR2C2 |
Protein Function
TTC6 has several biochemical functions, for example, RNA binding,RNA polymerase II core promoter proximal region sequence-specific DNA binding,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TTC6 itself. We selected most functions TTC6 had, and list some proteins which have the same functions with TTC6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | HIST2H3A,MEOX2,DLX4,NPAS4,NR3C1,ZSCAN21,MAX,BATF2,TCF4,FEZF2 |
| protein binding | KLF15,EML1,CTLA4,PRDX1,BFAR,RCC1,MED6,RPS14,SLC3A2,NGF |
| transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | TFAP4,NR5A2,NFYC,OTX1,HOXA10,GLIS2,FOXD1,GATA3,NR1H4,EGR2 |
| RNA binding | OAS1B,QKI2,RPL30,RPL18A,CPSF2,MIF4GDA,RBMY1B,HNRNPA1,RPS9,ZRANB2 |
| poly(A) RNA binding | FDPS,DIAP1,MRPS23,THUMPD1,DIAPH1,CNOT1,EIF3A,PDCD11,IGF2BP2,PRAC |
| single-stranded DNA binding | DMC1,LRPPRC,FUBP1,ERCC1,HMGB1,PURA,CDC45,RAD51C,HNRNPA1,SWSAP1 |
Interacting Protein
TTC6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TTC6 here. Most of them are supplied by our site. Hope this information will be useful for your research of TTC6.
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References
- Toyoda, A; Iio, W; et al. Isolation and Identification of Cellulose-Binding Proteins from Sheep Rumen Contents. APPLIED AND ENVIRONMENTAL MICROBIOLOGY 75:1667-1673(2009).
- Vural, B; Demirkan, A; et al. Seroreactivity against PTEN-induced putative kinase 1 (PINK1) in Turkish patients with Behcet's disease. CLINICAL AND EXPERIMENTAL RHEUMATOLOGY 27:S67-S72(2009).
