UGT2A3

Official Full Name

UDP glucuronosyltransferase 2 family, polypeptide A3
Synonyms

UGT2A3; UDP glucuronosyltransferase 2 family, polypeptide A3; UDP-glucuronosyltransferase 2A3; FLJ21934; UDP glucuronosyltransferase 2 family polypeptide A3; UDP glucuronosyltransferase 2A3; UDPGT 2A3;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rhesus Macaque
Zebrafish

Source

HEK293
Mammalian Cell

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	UGT2A3-1879HCL	Recombinant Human UGT2A3 cell lysate		Non	Inquiry
Mouse	UGT2A3-17814M	Recombinant Mouse UGT2A3 Protein	Mammalian Cell	His	Inquiry
Mouse	UGT2A3-9893M-B	Recombinant Mouse UGT2A3 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Mouse	UGT2A3-9893M	Recombinant Mouse UGT2A3 Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi	Inquiry
Rhesus Macaque	UGT2A3-5100R	Recombinant Rhesus monkey UGT2A3 Protein, His-tagged	Mammalian Cell	His	Inquiry
Rhesus Macaque	UGT2A3-4913R	Recombinant Rhesus Macaque UGT2A3 Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi	Inquiry
Rhesus Macaque	UGT2A3-4913R-B	Recombinant Rhesus Macaque UGT2A3 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Zebrafish	UGT2A3-7723Z	Recombinant Zebrafish UGT2A3	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

UGT2A3 involved in several pathways and played different roles in them. We selected most pathways UGT2A3 participated on our site, such as Pentose and glucuronate interconversions, Ascorbate and aldarate metabolism, Steroid hormone biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with UGT2A3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Pentose and glucuronate interconversions	UGT1A6;GKUP;ALDH2;UGT2B15;DHDHL;UGT1A6A;ALDH3A2A;DCXR;AKR1B10
Ascorbate and aldarate metabolism	ALDH9A1A.1;UGT1A1;UGT2A1;UGT5G1;ALDH2.1;UGT1A6B;UGDH;UGT1A6;UGT1A7
Steroid hormone biosynthesis	UGT1AB;CYP2C39;CYP7B1;HSD3B5;UGT2B15;HSD3B4;CYP3A25;HSD17B3;HSD17B12
Starch and sucrose metabolism	AMY1B;AMY1A;GBE1;PYGL;UGT2B15;GPI1;AGLA;SI;GBA3
Retinol metabolism	UGT1A1;UGT2A1;CYP2C70;CYP3A65;CYP3A41B;CYP3A7;DHRS4;CYP2C18;UGT1A7C
Porphyrin and chlorophyll metabolism	HMOX1A;BLVRB;UGT2A3;UGT2A1;EPRS;UGT1A4;UGT2B7;UROS;P22
Metabolism of xenobiotics by cytochrome P	GSTP2;GSTA2;GSTM5;UGT2B7;UGT1A3;UGT1A6A;GSTA;MGST1.1;CYP1A
Drug metabolism - cytochrome P	GSTM6;GSTM7;GSTM5;FMO4;ALDH3B2;GSTA3;FMO5;UGT1A6;MGST3
Drug metabolism - other enzymes	PNAT10;GMPS;TPMT;CES1;UCK2B;UGT2A3;UGT1A6B;UGT1A6;CDA
Metabolic pathways	PLCB2;GULO;AMDHD1;DPYD;Nat3;ACSL4;GRHPRB;UGDH;GAD2
Chemical carcinogenesis	UGT1A6;FAM84B;CYP2C38;UGT1A6B;ALDH3B1;CYP2C19;ALDH1A3;CYP3A4;CYP2C54

UGT2A3 has several biochemical functions, for example, glucuronosyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UGT2A3 itself. We selected most functions UGT2A3 had, and list some proteins which have the same functions with UGT2A3. You can find most of the proteins on our site.

Function	Related Protein
glucuronosyltransferase activity	UGT2A5;UGT3A2;UGT5A2;UGT2B15;UGT5E1;UGT5F1;UGT5B3;UGT1A2;UGT1A6B

UGT2A3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UGT2A3 here. Most of them are supplied by our site. Hope this information will be useful for your research of UGT2A3.

Research Area

Perreault, M; Gauthier-Landry, L; et al. The Human UDP-Glucuronosyltransferase UGT2A1 and UGT2A2 Enzymes Are Highly Active in Bile Acid Glucuronidation. DRUG METABOLISM AND DISPOSITION 41:1616-1620(2013).

Hardwick, RN; Ferreira, DW; et al. Altered UDP-Glucuronosyltransferase and Sulfotransferase Expression and Function during Progressive Stages of Human Nonalcoholic Fatty Liver Disease. DRUG METABOLISM AND DISPOSITION 41:554-561(2013).