USP4 Protein


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Official Full Name ubiquitin specific peptidase 4 (proto-oncogene)
Background Ubiquitinating enzymes (UBEs) catalyze protein ubiquitination, a reversible process countered by deubiquitinating enzyme (DUB) action. Five DUB subfamilies are recognized, including the USP, UCH, OTU, MJD, and JAMM enzymes. USP4 was originally identified
Synonyms USP4; ubiquitin specific peptidase 4 (proto-oncogene); ubiquitin specific protease 4 (proto oncogene) , UNP; ubiquitin carboxyl-terminal hydrolase 4; Unph; ubiquitin thioesterase 4; deubiquitinating enzyme 4; ubiquitin thiolesterase 4; ubiquitous nuclear;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Insect Cell
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • His (Fc)-Avi
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human USP4-183H Active Recombinant Human USP4, His-tagged E.coli His Inquiry
    Human USP4-42H Active Recombinant Human USP4 protein, His-tagged Insect Cell His Inquiry
    Human USP4-156H Recombinant Human USP4 Insect Cell N/A Inquiry
    Mouse USP4-17928M Recombinant Mouse USP4 Protein Mammalian Cell His Inquiry
    Rat USP4-6477R Recombinant Rat USP4 Protein Mammalian Cell His Inquiry
    Chicken USP4-1286C Recombinant Chicken USP4 Mammalian Cell His Inquiry
    Human USP4-456HCL Recombinant Human USP4 293 Cell Lysate HEK293 N/A Inquiry
    Human USP4-1253H Recombinant Human USP4 protein, GST-tagged E.coli GST Inquiry
    Rat USP4-6133R Recombinant Rat USP4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi Inquiry
    Mouse USP4-9965M Recombinant Mouse USP4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi Inquiry
    Human USP4-1915H Recombinant Human USP4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK Inquiry
    Human USP4-359H Recombinant Human USP4 Protein, GST-tagged E.coli GST Inquiry
    Mouse Usp4-6879M Recombinant Mouse Usp4 Protein, Myc/DDK-tagged HEK293T Myc/DDK Inquiry

    USP4 involved in several pathways and played different roles in them. We selected most pathways USP4 participated on our site, such as Death Receptor Signalling, Regulation of TNFR1 signaling, Signal Transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with USP4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Death Receptor Signalling OTULIN; TAX1BP1B; USP2; GNB2L1; OTUD7B; TAX1BP1; SHRPRBCK1R; OTULINB; RNF31; FAM105B
    Regulation of TNFR1 signaling SHARPIN; RBCK1; OTUD7B; USP2; USP4; OTULINB; TAX1BP1B; FAM105B; CLIP3; OTULIN
    Signal Transduction SPRY1; MKL1; OR2AP1; MYO9B; CDC42EP5; ROPN1; NEDD8; CRABP2A; EDNRAB; KAL1
    TNFR1-induced NFkappaB signaling pathway RNF31; SHRPRBCK1R; USP4; OTUD7B; SHARPIN; USP2
    TNFR1-induced proapoptotic signaling USP2; USP4; OTUD7B

    USP4 has several biochemical functions, for example, adenosine receptor binding, cysteine-type endopeptidase activity, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by USP4 itself. We selected most functions USP4 had, and list some proteins which have the same functions with USP4. You can find most of the proteins on our site.

    Function Related Protein
    adenosine receptor binding USP4; CECR1; CECR1A
    cysteine-type endopeptidase activity CTS7; USP15; USP34; USP6; CASP3B; CASP6; CASP3A; SFRP1; CTSL.1; CASP9
    identical protein binding MMP9; ZHX2; SMAD3; C1QL2; MYOM1; CORO1B; RASSF1; DIAP1; PLN; TRIM8
    metal ion binding RAB11FIP3; ADIPOR2; ITGA3; ACY1; SIAH2L; ZNF443; AOX3L1; MARCH9; LMO7A; CYCS
    protein binding MEMO1; MAPK1; EIF2A; POLD4; CAPNS2; EXOSC2; CDC26; CAMK2A; MEIOB; FOXR1
    ubiquitin-specific protease activity USP48; USP44; USP25; USP1; BRCC3; OTUD7A; USP20; UCHL5; USP33; USP5

    USP4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with USP4 here. Most of them are supplied by our site. Hope this information will be useful for your research of USP4.


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