USP43 involved in several pathways and played different roles in them. We selected most pathways USP43 participated on our site, such as DNA Damage Bypass, DNA Repair, Termination of translesion DNA synthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with USP43 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name |
Pathway Related Protein |
| DNA Damage Bypass |
POLI; USP10; ZBTB32; USP43A; UBE2L6; USP43; DTL; DDB1; KIAA0101; POLD3 |
| DNA Repair |
THRSP; COPS2; DDB1; TIMELESS; RIF1; ELL; ASCC2; ACTL6A; HUS1; ZFP830 |
| Termination of translesion DNA synthesis |
USP43; USP43A; POLI; KIAA0101; USP10 |
| Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template |
USP43A; POLI; USP43; KIAA0101; SPRTN; USP10 |
USP43 has several biochemical functions, for example, cysteine-type endopeptidase activity, cysteine-type peptidase activity, hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by USP43 itself. We selected most functions USP43 had, and list some proteins which have the same functions with USP43. You can find most of the proteins on our site.
| Function |
Related Protein |
| cysteine-type endopeptidase activity |
USP45; CTSL2; TINAG; USP17L2; ATG4D; USP1; USP27X; CTSC; USP33; USP51 |
| cysteine-type peptidase activity |
CASPBL; SENP3B; CAPN2B; CTSLA; CAPN3; CTSM; DUB1; CASP8; OTUD6B; UFSP2 |
| hydrolase activity |
MEIOB; HRASLS; EIF4A1B; Ren1; MTMR1B; PTPN2B; USPL1; OVCH2; REXO1; PRSS28 |
| peptidase activity |
PROCA; KLK7; HM13; MPND; C1RA; REN2; APH1C; PCSK5; CAPN3; CLCA3 |
| ubiquitin-specific protease activity |
OTUB1; USP2A; USP50; JOSD2; USP9; FAM105B; USP6; USP30; USP20; UCHL3 |
| ubiquitinyl hydrolase activity |
USP12A; USP54A; USP54; USP53; USP27X; USP43A; DUB1; USP9; USP2A; USP17L4 |
USP43 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with USP43 here. Most of them are supplied by our site. Hope this information will be useful for your research of USP43.
