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USP50

Official Full Name

ubiquitin specific peptidase 50
Synonyms

USP50; ubiquitin specific peptidase 50; ubiquitin specific protease 50; inactive ubiquitin carboxyl-terminal hydrolase 50; Inactive ubiquitin specific peptidase 50; inactive ubiquitin-specific peptidase 50;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Cynomolgus Monkey
Human

Source

HEK293
Insect Cell
Mammalian Cell

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	USP50-1897HCL	Recombinant Human USP50 cell lysate		Non		Inquiry
Human	USP50-0518H	Recombinant Human USP50 Protein (T2-A339), Tag Free	Insect Cell	Non	T2-A339	Inquiry
Human	USP50-0517H	Recombinant Human USP50 Protein (T2-A339), GST tagged	Insect Cell	GST	T2-A339	Inquiry
Cynomolgus Monkey	USP50-1083C	Recombinant Cynomolgus USP50 Protein, His-tagged	Mammalian Cell	His		Inquiry
Cynomolgus Monkey	USP50-826C	Recombinant Cynomolgus Monkey USP50 Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Cynomolgus Monkey	USP50-826C-B	Recombinant Cynomolgus Monkey USP50 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

USP50 involved in several pathways and played different roles in them. We selected most pathways USP50 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with USP50 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

USP50 has several biochemical functions, for example, cysteine-type endopeptidase activity, ubiquitin-specific protease activity. Some of the functions are cooperated with other proteins, some of the functions could acted by USP50 itself. We selected most functions USP50 had, and list some proteins which have the same functions with USP50. You can find most of the proteins on our site.

Function	Related Protein
cysteine-type endopeptidase activity	CTSK;CASP7;USP16;CASP14;UCHL1;CTSSA;CTLA2B;USP24;CASP1
ubiquitin-specific protease activity	VCPIP1;OTUD5A;USP40;USP27X;EIF3F;BAP1;USP22;DUB1;USP5

USP50 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with USP50 here. Most of them are supplied by our site. Hope this information will be useful for your research of USP50.

IPO5; UMPS; ACADM; IGF2R; ABCD3; BSG; ALDH3A2; ABCE1; GNB2; CKAP4; SLC1A5; MTHFD1L; TUBA1A; HUWE1; DYNC2H1; NUP205; AMBRA1; LUC7L; SLC25A13; AFG3L2

Research Area

Armando, I; Villar, VM; et al. Dopamine D3 receptor inhibits the ubiquitin-specific peptidase 48 to promote NHE3 degradation. FASEB JOURNAL 28:1422-1434(2014).

Bermejo, JL; Kabisch, M; et al. Exploring the association between genetic variation in the SUMO isopeptidase gene USPL1 and breast cancer through integration of data from the population-based GENICA study and external genetic databases. INTERNATIONAL JOURNAL OF CANCER 133:362-372(2013).