VPRBP

  • Official Full Name

    Vpr (HIV-1) binding protein

  • Overview

    VprBP may act as a receptor for CUL4-DDB1 ubiquitin ligase complex. In case of HIV1 infection, this protein is recruited by HIV1 VPR protein which is believed to result in an arrest of the cell cyccle in the G2 phase.

  • Synonyms

    VPRBP;Vpr (HIV-1) binding protein;DCAF1;protein VPRBP;Vpr-binding protein;vpr-interacting protein;HIV-1 Vpr-binding protein;DDB1 and CUL4 associated factor 1;DDB1- and CUL4-associated factor 1;serine/threonine-protein kinase VPRBP
Cat.# Product name Source (Host) Species Tag Protein Length Price
VPRBP-18354M Recombinant Mouse VPRBP Protein Mammalian Cells Mouse His
VPRBP-10055M Recombinant Mouse VPRBP Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
VPRBP-10055M-B Recombinant Mouse VPRBP Protein Pre-coupled Magnetic Beads HEK293 Mouse
VPRBP-1088H Recombinant Human VPRBP protein, His-tagged E.coli Human His 1045-1396aa

    Involved Pathway

    VPRBP involved in several pathways and played different roles in them. We selected most pathways VPRBP participated on our site, such as Adaptive Immune System,Antigen processing: Ubiquitination &amp,Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with VPRBP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Immune System TRIM26,PRLRB,ABI1,S100A12,WSB1,ATG7,SUGT1,ASB13,MICA,SIGIRR
    Adaptive Immune System ASB10,LILRB2,LILRA1,AP2A2,SIGLEC6,KIF15,IGKC,KLHL20,CREB1B,FGF18B
    mRNA processing SRSF10,RNASET2B,PPM1G,RBM12B1,PRPF4B,DDX39,Ankar,FAM120B,DHX15,LSMD1
    Antigen processing: Ubiquitination &amp TPP2,HECTD3,ASB10,UBE2V1,ASB13,FBXO17,UFL1,ASB18,KLHL20,UBE2E3
    presentation FBXO44,RNF34,RNF4,TRIM39,BLMH,SEC23A,TRAF7,ASB8,RNF19B,RNF220
    Class I MHC mediated antigen processing &amp TRIM63,UBR1,WSB1,CD207,SPSB4,ASB7,ERAP1,TRIM9,CTSS,TRIM39
    Proteasome degradation UBE2L6,ASB6,TRIM9,ASB18,HECTD3,DZIP3,TRIM69,PJA1,WWP1,ASB9

    Protein Function

    VPRBP has several biochemical functions, for example, ATP binding,histone kinase activity (H2A-T120 specific),kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by VPRBP itself. We selected most functions VPRBP had, and list some proteins which have the same functions with VPRBP. You can find most of the proteins on our site.

    Function Related Protein
    kinase activity PIP5K2,CDC7,TNK2B,CLK4B,DNAJC3B,MASTL,TSSK5,LTK,IRAK1,BSK146
    nucleotide binding RCAN2,SRSF2B,BMPR1BA,GIMAP3,TYMS,HNRNPDL,DHX57,ARL15A,PPARGC1A,RPS6KA3A
    ATP binding KCNJ10,GLULA,KIF4A,TEK,NLRC5,TRIO,HSPA7,TARS,ABCA6,EIF2AK2
    protein serine/threonine kinase activity MARK4,ALPK2,MAP4K4,MAPK12B,CSNK1G1,GAK,ADCK1,SLK,TTBK2,MAP4K2
    transferase activity PRDM11,PRKCHB,CAMK1DA,PRDM6,EPHA2A,UGT2B3,UCKL1A,UGT2B5,TGM2B,CKMT2A

    Interacting Protein

    VPRBP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VPRBP here. Most of them are supplied by our site. Hope this information will be useful for your research of VPRBP.

    Rpgrip1l

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