VPS11 Protein

VPS11

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VPS11

Official Full Name vacuolar protein sorting 11 homolog (S. cerevisiae)
Background Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps11 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway.
Synonyms VPS11; vacuolar protein sorting 11 homolog (S. cerevisiae); vacuolar protein sorting 11 (yeast homolog); vacuolar protein sorting-associated protein 11 homolog; PEP5; RNF108; END1; HGNC:14583; hVPS11; RING finger protein 108; Vacuolar protein sorting 11 (yeast); Vacuolar protein sorting associated protein 11 homolog; Vacuolar protein sorting protein 11
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293T
    • Mammalian Cell
    • Tag :
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human VPS11-30026TH Recombinant Human VPS11, His-tagged E.coli His
    Human VPS11-3669H Recombinant Human VPS11, His-tagged E.coli His
    Mouse VPS11-18358M Recombinant Mouse VPS11 Protein Mammalian Cell His
    Zebrafish VPS11-3599Z Recombinant Zebrafish VPS11 Mammalian Cell His
    Human VPS11-1911HCL Recombinant Human VPS11 cell lysate N/A
    Human VPS11-687H Recombinant Human VPS11 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Vps11-6930M Recombinant Mouse Vps11 Protein, Myc/DDK-tagged HEK293T Myc/DDK

    VPS11 involved in several pathways and played different roles in them. We selected most pathways VPS11 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with VPS11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    VPS11 has several biochemical functions, for example, nucleotide binding, protein binding, protein domain specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by VPS11 itself. We selected most functions VPS11 had, and list some proteins which have the same functions with VPS11. You can find most of the proteins on our site.

    Function Related Protein
    nucleotide binding NT5C3A; APAF1; HNRNPA1B; HNRPLL; HSP90AA1.1; GNA13A; TLK1A; CLPXA; ABCA4A; PKZ
    protein binding MYO5B; GALR1; TJAP1; HEATR5B; CHD7; MASP1; YWHAH; PODXL; TAB1; HAX1
    protein domain specific binding VRK2; HIST2H4; TJP1; SORBS2; SCAF1; VCP; XPO1; STX1A; HOMER2; ICA1
    syntaxin binding NAPAA; CPLX4C; STX6; SYT4; VAMP7; SYT10; STXBP5A; TMED10; SYTL4; RPH3A
    zinc ion binding PMPCB; NANOS3; ZDHHC20A; MAN2A1; ANAPC11; KDM7AB; APOBEC3D; MEX3B; GTF2H2C; APOBEC3F

    VPS11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VPS11 here. Most of them are supplied by our site. Hope this information will be useful for your research of VPS11.

    VPS18; VPS16; Vps33a; 386682

    Sato, TK; Rehling, P; et al. Class C Vps protein complex regulates vacuolar SNARE pairing and is required for vesicle docking/fusion. MOLECULAR CELL 6:661-671(2000).

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