VPS24
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Official Full Name
Vacuolar Protein Sorting 24 homolog (S. cerevisiae)
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Overview
This gene encodes a protein that sorts transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ring finger protein 103 (RNF103) gene. -
Synonyms
VPS24; vacuolar protein sorting 24 homolog (S. cerevisiae); NEDF; CHMP3; CGI-149; FLJ38114; charged multivesicular body protein 3; 25.1 protein; OTTHUMP00000203324; OTTHUMP00000203325; OTT- HUMP00000203326; CHMP family, member 3; chro- matin-modifying protein 3; neuroendocrine differentiation factor; vacuolar protein sorting-associated protein 24; hVps24; vacuolar protein sorting 24 (yeast); Neur- oendocrine differentiation factor; Vacuolar protein sorting-associated protein 24;
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | VPS24-3561H | Recombinant Human VPS24, His-tagged | E.coli | His |
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| Human | VPS24-3671H | Recombinant Human VPS24, GST-tagged | E.coli | GST | 1-222aa | |
| Human | VPS24-396HCL | Recombinant Human VPS24 293 Cell Lysate | HEK293 | Non |
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- Involved Pathway
- Protein Function
- Interacting Protein
VPS24 involved in several pathways and played different roles in them. We selected most pathways VPS24 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with VPS24 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Endocytosis | HSPA1A;PSD4;CCR5;WIPF2;PIP5KL1;KIF5A;SH3GLB2;ASAP1A;IGF1RB |
VPS24 has several biochemical functions, for example, phosphatidylcholine binding, protein binding, protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by VPS24 itself. We selected most functions VPS24 had, and list some proteins which have the same functions with VPS24. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| phosphatidylcholine binding | CHMP3;APOA4B.1;ESYT2;SERPINA5;CETP;APOA4;PCTP;RASGRP1;GPR12 |
| protein binding | FAM21C;CUL2;GM885;IL7R;CCDC28B;MKRN1;RAB6B;DHX8;RXRG |
| protein homodimerization activity | ID1;TBX15;SLC4A1;RPS19;ECE1;IDH1;TKT;GRPEL1;FGFR1OP2 |
| ubiquitin-specific protease binding | MARCH6;PARK2;AMFR;BAG6;CHMP3;PARK7;RAD23A;VCP;DERL1 |
VPS24 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VPS24 here. Most of them are supplied by our site. Hope this information will be useful for your research of VPS24.
STAMBP; USP8; USP54; FOS; Chmp3; VAV2; SMAD1; SMAD5; Nedd1; ATP6V1A; Vps4b; Tsg101; Ptpn23
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