VPS37C
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Official Full Name
vacuolar protein sorting 37 homolog C (S. cerevisiae) -
Overview
VPS37C is a subunit of ESCRT-I (endosomal sorting complex required for transport I), a complex in the class E vacuolar;protein sorting (VPS) pathway required for sorting ubiquitinated transmembrane proteins into internal vesicles of;multivesicular bodies (Eastman et al., 2005 (PubMed 15509564)). -
Synonyms
VPS37C;vacuolar protein sorting 37 homolog C (S. cerevisiae);vacuolar protein sorting 37C (yeast);vacuolar protein sorting-associated protein 37C;FLJ20847;5730409F24Rik;AU042646;ESCRT I complex subunit VPS37C;ESCRT-I complex subunit VPS37C;hVps37C;PML39;RGD1309258;Vacuolar protein sorting 37C;Vacuolar protein sorting associated protein 37C;VP37C_HUMAN;OTTHUMP00000236974;OTTHUMP00000236975
Recombinant Proteins
- Human
- Mouse
- Chicken
- Zebrafish
- E.coli
- Mammalian Cells
- HEK293
- His
- Avi
- Fc
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| VPS37C-3902H | Recombinant Human VPS37C protein, His-tagged | E.coli | Human | His | 1-117 aa | |
| VPS37C-18376M | Recombinant Mouse VPS37C Protein | Mammalian Cells | Mouse | His |
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| VPS37C-4393C | Recombinant Chicken VPS37C | Mammalian Cells | Chicken | His |
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| VPS37C-4861Z | Recombinant Zebrafish VPS37C | Mammalian Cells | Zebrafish | His |
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| VPS37C-10068M | Recombinant Mouse VPS37C Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| VPS37C-10068M-B | Recombinant Mouse VPS37C Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| VPS37C-7844H | Recombinant Human VPS37C protein, GST-tagged | E.coli | Human | GST |
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Involved Pathway
VPS37C involved in several pathways and played different roles in them. We selected most pathways VPS37C participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with VPS37C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Endocytosis | ARPC1B,ZFYVE20,ARPC2,ZFYVE27,ARPC5B,ZFYVE16,SNX3,RAB11B,IGF1RA,HSPA2 |
Protein Function
VPS37C has several biochemical functions, for example, calcium-dependent protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by VPS37C itself. We selected most functions VPS37C had, and list some proteins which have the same functions with VPS37C. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calcium-dependent protein binding | TNNI3,S100A4,MYO5A,SYT1,STX1A,CPNE3,DMBT1,ANXA2,FCN2,CALM3 |
Interacting Protein
VPS37C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VPS37C here. Most of them are supplied by our site. Hope this information will be useful for your research of VPS37C.
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References
- Stefani, F; Zhang, L; et al. UBAP1 Is a Component of an Endosome-Specific ESCRT-I Complex that Is Essential for MVB Sorting. CURRENT BIOLOGY 21:1245-1250(2011).
- Okumura, M; Katsuyama, AM; et al. VPS37 Isoforms Differentially Modulate the Ternary Complex Formation of ALIX, ALG-2, and ESCRT-I. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 77:1715-1721(2013).
