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VPS37C

Official Full Name

vacuolar protein sorting 37 homolog C (S. cerevisiae)
Overview

VPS37C is a subunit of ESCRT-I (endosomal sorting complex required for transport I), a complex in the class E vacuolar;protein sorting (VPS) pathway required for sorting ubiquitinated transmembrane proteins into internal vesicles of;multivesicular bodies (Eastman et al., 2005 (PubMed 15509564)).
Synonyms

VPS37C; vacuolar protein sorting 37 homolog C (S. cerevisiae); vacuolar protein sorting 37C (yeast); vacuolar protein sorting-associated protein 37C; FLJ20847; 5730409F24Rik; AU042646; ESCRT I complex subunit VPS37C; ESCRT-I complex subunit VPS37C; hVps37C; PML39; RGD1309258; Vacuolar protein sorting 37C; Vacuolar protein sorting associated protein 37C; VP37C_HUMAN; OTTHUMP00000236974; OTTHUMP00000236975;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Zebrafish

Source

E.coli
HEK293
Mammalian Cell

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	VPS37C-3902H	Recombinant Human VPS37C protein, His-tagged	E.coli	His	1-117 aa	$319 / 25μg
Mouse	VPS37C-18376M	Recombinant Mouse VPS37C Protein	Mammalian Cell	His		Inquiry
Mouse	VPS37C-10068M	Recombinant Mouse VPS37C Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Mouse	VPS37C-10068M-B	Recombinant Mouse VPS37C Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	VPS37C-4861Z	Recombinant Zebrafish VPS37C	Mammalian Cell	His		Inquiry
Chicken	VPS37C-4393C	Recombinant Chicken VPS37C	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

VPS37C involved in several pathways and played different roles in them. We selected most pathways VPS37C participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with VPS37C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Endocytosis	IGF1R;WIPF1A;AP2M1A;TGFB1;CAPZA1A;CHMP1B;DNM2A;RAB35B;ARPC5B

VPS37C has several biochemical functions, for example, calcium-dependent protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by VPS37C itself. We selected most functions VPS37C had, and list some proteins which have the same functions with VPS37C. You can find most of the proteins on our site.

Function	Related Protein
calcium-dependent protein binding	MYO1D;STX1A;ANXA6;KOP;CHP;MASP1;MYO5A;S100PBP;TNNT3

VPS37C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VPS37C here. Most of them are supplied by our site. Hope this information will be useful for your research of VPS37C.

Dock1

Research Area

Okumura, M; Katsuyama, AM; et al. VPS37 Isoforms Differentially Modulate the Ternary Complex Formation of ALIX, ALG-2, and ESCRT-I. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY 77:1715-1721(2013).

Stefani, F; Zhang, L; et al. UBAP1 Is a Component of an Endosome-Specific ESCRT-I Complex that Is Essential for MVB Sorting. CURRENT BIOLOGY 21:1245-1250(2011).