VPS8 involved in several pathways and played different roles in them. We selected most pathways VPS8 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with VPS8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name |
Pathway Related Protein |
VPS8 has several biochemical functions, for example, protein binding, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by VPS8 itself. We selected most functions VPS8 had, and list some proteins which have the same functions with VPS8. You can find most of the proteins on our site.
| Function |
Related Protein |
| protein binding |
PTPN11A; RGP1; CEP76; SERPING1; SORBS3; PLK1S1; CA; TBC1D15; FAM59A; MPZL2 |
| zinc ion binding |
PRDM2; CAR5A; EP300; SHPRH; BIRC8; CIZ1B; NR5A1; DDX58; ZDHHC21; MAN2C1 |
VPS8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with VPS8 here. Most of them are supplied by our site. Hope this information will be useful for your research of VPS8.
TGFBRAP1; SMAD9; RAB5C
Klinger, CM; Klute, MJ; et al. Comparative Genomic Analysis of Multi-Subunit Tethering Complexes Demonstrates an Ancient Pan-Eukaryotic Complement and Sculpting in Apicomplexa. PLOS ONE 8:-(2013).
Epp, N; Ungermann, C; et al. The N-Terminal Domains of Vps3 and Vps8 Are Critical for Localization and Function of the CORVET Tethering Complex on Endosomes. PLOS ONE 8:-(2013).
