WDR3
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Official Full Name
WD repeat domain 3 -
Overview
This gene encodes a nuclear protein containing 10 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, which usually include a trp-asp at the C-terminal end. Proteins belonging to the WD repeat family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. -
Synonyms
WDR3;WD repeat domain 3;WD repeat-containing protein 3;DIP2;FLJ12796;UTP12;dJ776P7.2 (WD repeat domain 3)
Recombinant Proteins
- Mouse
- Chicken
- Rhesus macaque
- Zebrafish
- Mammalian Cells
- HEK293
- His
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| WDR3-18463M | Recombinant Mouse WDR3 Protein | Mammalian Cells | Mouse | His |
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| WDR3-3132C | Recombinant Chicken WDR3 | Mammalian Cells | Chicken | His |
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| WDR3-5196R | Recombinant Rhesus monkey WDR3 Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| WDR3-9863Z | Recombinant Zebrafish WDR3 | Mammalian Cells | Zebrafish | His |
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| WDR3-10127M | Recombinant Mouse WDR3 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| WDR3-10127M-B | Recombinant Mouse WDR3 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| WDR3-5009R | Recombinant Rhesus Macaque WDR3 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | Avi&Fc&His |
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| WDR3-5009R-B | Recombinant Rhesus Macaque WDR3 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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Involved Pathway
WDR3 involved in several pathways and played different roles in them. We selected most pathways WDR3 participated on our site, such as Ribosome biogenesis in eukaryotes, which may be useful for your reference. Also, other proteins which involved in the same pathway with WDR3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ribosome biogenesis in eukaryotes | NAT10,NHP2L1,WDR36,GAR1,NHP2L1A,XPO1,MPHOSPH10,LOC81691,WDR75,cka1 |
Protein Function
WDR3 has several biochemical functions, for example, poly(A) RNA binding,snoRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by WDR3 itself. We selected most functions WDR3 had, and list some proteins which have the same functions with WDR3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | DDX55,GTL3,IFIT2,TNS1,WIBG,NSUN2,Api5,PUM2,FAM98C,PABPC4 |
| snoRNA binding | UTP15,DDX21,NUDT4,NUDT16,HEATR1,NUDT5,UTP6,NHP2,IMP4,NUDT1 |
Interacting Protein
WDR3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WDR3 here. Most of them are supplied by our site. Hope this information will be useful for your research of WDR3.
Resources
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References
- Saeki, M; Egusa, H; et al. Exosome-Bound WD Repeat Protein Monad Inhibits Breast Cancer Cell Invasion by Degrading Amphiregulin mRNA. PLOS ONE 8:-(2013).
- Teng, YN; Liao, MH; et al. Expression of lrwd1 in mouse testis and its centrosomal localization. INTERNATIONAL JOURNAL OF ANDROLOGY 33:832-840(2010).
