WDR34 involved in several pathways and played different roles in them. We selected most pathways WDR34 participated on our site, such as Assembly of the primary cilium, Intraflagellar transport, Organelle biogenesis and maintenance, which may be useful for your reference. Also, other proteins which involved in the same pathway with WDR34 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name |
Pathway Related Protein |
| Assembly of the primary cilium |
BBS2; WDR34; IFT-20; DCTN1A; PLK4; EXOC6; IFT122; OST4; TTC30A1; BBS1 |
| Intraflagellar transport |
HSPB11; KIF3CB; DYNLL2A; DYF-1; WDR35; TTC30A1; KIF3B; FLR; IFT46; IFT52 |
| Organelle biogenesis and maintenance |
RABL5; LZTFL1; OST4; PKD2; IFT74; ATAT1; DYNLRB1; NPHP3; BBS4; SCLT1 |
WDR34 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by WDR34 itself. We selected most functions WDR34 had, and list some proteins which have the same functions with WDR34. You can find most of the proteins on our site.
| Function |
Related Protein |
| protein binding |
DHX30; SPDYE2; TEK; STAMBP; SYCE2; UCN; TRIM25; ALOX5AP; CUL2; AIDA |
WDR34 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WDR34 here. Most of them are supplied by our site. Hope this information will be useful for your research of WDR34.
COIL; TRIM54; Dynll1; MAPK6; Dynlrb1
Asante, D; Stevenson, NL; et al. Subunit composition of the human cytoplasmic dynein-2 complex. JOURNAL OF CELL SCIENCE 127:4774-4787(2014).
Goggolidou, P; Stevens, JL; et al. ATMIN is a transcriptional regulator of both lung morphogenesis and ciliogenesis. DEVELOPMENT 141:3966-3977(2014).
