WNT2

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WNT2

Official Full Name wingless-type MMTV integration site family member 2
Synonyms WNT2; wingless-type MMTV integration site family member 2; INT1L1; protein Wnt-2; IRP; secreted growth factor; int-1-like protein 1; Int-1-related protein
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E. coli
    • E.coli
    • HEK293
    • Insect Cell
    • Mammalian Cell
    • Yeast
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human WNT2-115H Recombinant Human WNT2 Protein E. coli
    Human WNT2-2264H Recombinant Human WNT2 protein, His-tagged Insect Cell His
    Mouse Wnt2-4631M Recombinant Mouse Wnt2 protein, His-tagged E.coli His
    Human WNT2-1893H Recombinant Human WNT2 protein, His-tagged E.coli His
    Human WNT2-2217H Recombinant Human WNT2 Protein (26-360 aa), His-tagged Yeast His
    Human WNT2-298HCL Recombinant Human WNT2 293 Cell Lysate HEK293 N/A
    Mouse WNT2-18568M Recombinant Mouse WNT2 Protein Mammalian Cell His
    Rhesus Macaque WNT2-5218R Recombinant Rhesus monkey WNT2 Protein, His-tagged Mammalian Cell His
    Zebrafish WNT2-8589Z Recombinant Zebrafish WNT2 Mammalian Cell His

    WNT2 involved in several pathways and played different roles in them. We selected most pathways WNT2 participated on our site, such as Wnt signaling pathway, Hedgehog signaling pathway, Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with WNT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Wnt signaling pathway BAMBI; FBXW11A; SIAH1A; PPP3R2; WNT7B; NLK1; PORCNL; FZD7A; SFRP5; DKK1B
    Hedgehog signaling pathway WNT2B; CSNK1G2A; WNT9A; SAP18; HHIP; WNT2BA; IHH; GSK3B; WNT7A; PRKACA
    Hippo signaling pathway FZD3; WWTR1; FRMD6; AJUBA; MOBKL1A; WNT11; SMAD4; CRB1; WNT8B; WWC1
    Signaling pathways regulating pluripotency of stem cells WNT3; NODAL; ACVR2A; ID2; INHBB; PCGF5; FGFR4; FZD3; PIK3R3; WNT8B
    Melanogenesis GNAO1A; PRKACAA; TYR; FZD10; FZD8; GNAO1; WNT16; WNT2; Adcy4; LEF1
    HTLV-I infection FZD10; DVL2; WNT10B; DLG1; DVL1; ANAPC2; POLD1; RANBP1; H2-AB1; CALR
    Pathways in cancer TRP53; PTCH1; MAX; SOS1; FH1; Adcy4; FZD1; PIK3R2; GNAI2; MAPK10
    Proteoglycans in cancer IGF1R; PRKACB; FZD9; ITGA5; PRKCB; HIF1A; SDC4; CAMK2A; TWIST2; LUM
    Basal cell carcinoma Fzd4; FZD1; WNT11; FZD9; WNT4; GLI2; WNT2; FZD6; WNT3; SUFU

    WNT2 has several biochemical functions, for example, cytokine activity, frizzled binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by WNT2 itself. We selected most functions WNT2 had, and list some proteins which have the same functions with WNT2. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activity Ifna15; MSTNB; NODAL; CCL38A.4; NDP; IFNA2; CMTM2; IL10; IFNG; IFNB
    frizzled binding WNT2BB; WNT6; WNT8A; WNT16; WNT3A; WNT9A; MYOC; RNF43; RSPO3; LRP6
    protein binding FAM164C; KCNE3; UGGT1; LIPE; GTF3C6; KIF9; SLC4A1AP; MLLT10; SMUG1; SNRPE
    receptor agonist activity GREM1; WNT1; NODAL; GAS6; VEGFA; WNT5A; SFRP2; WNT2; WNT4; WNT3A

    WNT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WNT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of WNT2.

    SFRP1; UQCR11; HCK; AQP5; RRAGC

    Li, QS; Yu, P; et al. GENE EXPRESSION PROFILES OF VARIOUS CYTOKINES IN MESENCHYMAL STEM CELLS DERIVED FROM UMBILICAL CORD TISSUE AND BONE MARROW FOLLOWING INFECTION WITH HUMAN CYTOMEGALOVIRUS. CELLULAR & MOLECULAR BIOLOGY LETTERS 19:140-157(2014).
    Chen, J; Fu, L; et al. IDENTIFICATION OF ANTI-WNT2 MOUSE MONOCLONAL ANTIBODY AS A TARGETED ANTICANCER THERAPY IN ESOPHAGEAL SQUAMOUS CELL CARCINOMA. ANNALS OF ONCOLOGY 24:25-25(2013).

    WNT

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