Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

YWHAB

  • Official Full Name

    YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide

  • Overview

    14-3-3, a family of acidic and soluble proteins, highly conserved in amino acid sequences from yeast to mammals, is expressed in all eukaryotic cells. Seven isoforms(Beta, Gamma, Epsilon, Eta, Zeta, Sigma and Tau/Phi) encoded by seven distinct genes are identified in mammals and forms homo- and hetero- dimeric cupshaped structures. As 14-3-3 is interacted with more than 100 binding partners, it regulates key proteins involved in various biological processes such as signal transduction, cell cycle, transcriptional control, cell proliferation, apoptosis, and ion channel physiology. Most 14-3-3 requires phosphorylation of serine or threonine residues in the target sequence. This protein is abundantly expressed in the brain and has been detected in the cerebrospinal fluid of patients with different neurological disorders.
  • Synonyms

    YWHAB; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide; tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, alpha polypeptide , YWHAA; 14-3-3 protein beta/alpha; 14 3 3 alpha; 14 3 3 beta; 14-3-3 alpha; protein 1054; brain protein 14-3-3, beta isoform; protein kinase C inhibitor protein 1; protein kinase C inhibitor protein-1; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, alpha polypeptide; HS1; GW128; YWHAA; KCIP-1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Yeast
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • sumostar
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human YWHAB-4895H Recombinant Human Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein, Beta Polypeptide E.coli N/A
Human YWHAB-875H Recombinant Human YWHAB protein(Met1-Asn246), GST-tagged E. coli N-GST Met1-Asn246
Human YWHAB-103H Recombinant Human Tyrosine 3-monooxygenase/ Tryptophan 5-monooxygenase Activation Protein, Beta Polypeptide E.coli N/A
Human YWHAB-31136TH Recombinant Human YWHAB E.coli N/A
Human YWHAB-4894H Recombinant Human Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein, Beta Polypeptide, GST-tagged E.coli GST
Human YWHAB-3774H Recombinant Human YWHAB, GST-tagged E.coli GST 1-63aa
Human YWHAB-26001TH Recombinant Human YWHAB protein(Met1-Asn246) E. coli N/A Met1-Asn246
Human YWHAB-874H Recombinant Human YWHAB, None tagged E.coli N/A
Human YWHAB-26000TH Recombinant Human YWHAB E.coli N/A
Human YWHAB-162H Recombinant Human YWHAB, GST-tagged E.coli GST
Human YWHAB-31746TH Recombinant Human YWHAB E.coli N/A
Human YWHAB-135H Recombinant Human YWHAB Protein, His-tagged Insect Cell His
Human YWHAB-233HCL Recombinant Human YWHAB 293 Cell Lysate HEK293 N/A
Human YWHAB-234HCL Recombinant Human YWHAB 293 Cell Lysate HEK293 N/A
Human YWHAB-1959H Recombinant Human YWHAB Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human YWHAB-2377H-B Recombinant Human YWHAB Protein Pre-coupled Magnetic Beads HEK293
Human YWHAB-2377H Recombinant Human YWHAB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human YWHAB-1874HFL Recombinant Full Length Human YWHAB Protein, C-Flag-tagged Mammalian cells Flag
Mouse Ywhab-136M Recombinant Mouse Ywhab Protein, His-tagged Insect Cell His
Mouse Ywhab-7039M Recombinant Mouse Ywhab Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Ywhab-5820M Recombinant Mouse Ywhab protein, His-sumostar-tagged Yeast His-sumostar 1-246aa
Mouse Ywhab-4854M Recombinant Mouse Ywhab protein, His-tagged E.coli His 1-246aa
Mouse YWHAB-2401M Recombinant Mouse YWHAB Protein (1-246 aa), His-tagged Yeast His 1-246 aa
Rat YWHAB-6637R Recombinant Rat YWHAB Protein Mammalian Cell His
Rat YWHAB-6293R Recombinant Rat YWHAB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat YWHAB-6293R-B Recombinant Rat YWHAB Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus YWHAB-1170C Recombinant Cynomolgus YWHAB protein(Met2-Asn244) E. coli N/A Met2-Asn244
Rhesus Macaque YWHAB-5246R Recombinant Rhesus monkey YWHAB Protein, His-tagged Mammalian Cell His
Rhesus Macaque YWHAB-5059R-B Recombinant Rhesus Macaque YWHAB Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque YWHAB-5059R Recombinant Rhesus Macaque YWHAB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken YWHAB-1434C Recombinant Chicken YWHAB Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • YWHAB Related Articles

YWHAB involved in several pathways and played different roles in them. We selected most pathways YWHAB participated on our site, such as Cell cycle, Oocyte meiosis, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with YWHAB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cell cycleNUMA1;CHEK1;NUP50;TEX15;CCND1;MAD1L1;CDKN2B;CDK11B;TUBG2
Oocyte meiosisPPP2R5CB;MAPK12;IGF1RB;RPS6KA3;YWHAG;PPP3R1B;YWHAE2;MAPK3;ANAPC7
PIK-Akt signaling pathwayLAMB2;LPAR6;ITGAV;GNGT2;FGF7;CCNE2;COL6A6;PPP2R2A;FGFR4
Hippo signaling pathwayBMP2;AREG;TGFB3;SMAD2;SMAD3;WNT7A;NKD1;SMAD4;INADL
Hepatitis BTNF;MAPK10;TGFB1;IKBKB;MAP3K1;IFNA17;IFIH1;STAT4;PIK3CG
Epstein-Barr virus infectionPIK3CB;POLR3G;NEDD4;PSMD3;HLA-C;TRAF5;YWHAZ;HLA-A;HSPA1L
Viral carcinogenesisIKBKG;H2BFWT;HDAC4;GTF2A2;HIST2H4;CCND3;HIST1H2BL;VAC14;GRB2

YWHAB has several biochemical functions, for example, enzyme binding, histone deacetylase binding, phosphoprotein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by YWHAB itself. We selected most functions YWHAB had, and list some proteins which have the same functions with YWHAB. You can find most of the proteins on our site.

Function Related Protein
enzyme bindingC6orf211;RXRA;MSH2;CAT;PARK2;BCR;SCNM1-PS;CTNNBL1;CYB5A
histone deacetylase bindingBRMS1L;MAPK8;BCOR;RBBP4;DNMT3B;GCM1;HDAC5;KAT2A;PARK2
phosphoprotein bindingMID1;PRKCSH;GPRIN1;TOX3;YWHAE;PLAT;CACNB2;SFN;MID2
phosphoserine bindingYWHAB;PIN1;YWHAE;NEDD4
protein C-terminus bindingRAD51;SIRT1;ZBTB16;ATP2A2;MPDZ;HSPG2;OPRL1;SHANK3;MAP2K1
protein bindingMRTO4;CUEDC2;ZBP1;UBE2B;TMEM30B;FAM46A;SORBS2;ITGB3B;NDUFB10
protein complex bindingDAG1;THRA;SHANK1;AKAP5;CDK5RAP1;CASP8;YWHAB;NCKAP1;FADD
protein domain specific bindingHOMER2;FOXA1;TRIM11;CNOT1;NR0B2;HIST2H4;MRPS31;ICA1;SORBS2
transcription corepressor activitySOD3;TOB1;DNMT3B;SMYD1;NCOR1;CBFA2T2;ATF3;TRIB3;NEUROD2

YWHAB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with YWHAB here. Most of them are supplied by our site. Hope this information will be useful for your research of YWHAB.

RAF1; TSC2

Sun, YF; Liu, RR; et al. Genome-Wide Linkage Analysis and Association Study Identifies Loci for Polydactyly in Chickens. G3-GENES GENOMES GENETICS 4:1167-1172(2014).
van Rijn, SJ; Riemers, FM; et al. Expression Stability of Reference Genes for Quantitative RT-PCR of Healthy and Diseased Pituitary Tissue Samples Varies Between Humans, Mice, and Dogs. MOLECULAR NEUROBIOLOGY 49:893-899(2014).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All YWHAB Products

Required fields are marked with *

My Review for All YWHAB Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends