|Official Full Name||zinc fingers and homeoboxes 1|
|Background||The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 1 of this gene family. In addition to forming homodimers, this protein heterodimerizes with members 2 and 3 of the zinc fingers and homeoboxes family. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream chromosome 8 open reading frame 76 (C8orf76) gene.|
|Synonyms||ZHX1; zinc fingers and homeoboxes 1; zinc fingers and homeoboxes protein 1; ZHX 1; ZHX-1; ZHX1_HUMAN; Zinc finger and homeodomain protein 1; Zinc fingers and homeobox 1; OTTHUMP00000228386; OTTHUMP00000228389|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
zhx1 involved in several pathways and played different roles in them. We selected most pathways zhx1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with zhx1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
zhx1 has several biochemical functions, for example, DNA binding, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by zhx1 itself. We selected most functions zhx1 had, and list some proteins which have the same functions with zhx1. You can find most of the proteins on our site.
|DNA binding||KMT2A; POLR2K; ZFP553; PIAS1; THAP3; HNRPK; PHF5A; NUSAP1; APP; PROX1A|
|metal ion binding||HCCS; CYP1A; LMAN1; PPP1CC; TRIM50; TERT; RNF222; TPP1; ZNF750; NME2|
|protein binding||PLGRKT; CCDC137; ERCC6L; STAT3; SHMT2; BRSK1; CDC5L; IKBKE; MCM7; EHMT1|
|protein heterodimerization activity||BCL2A; ENO3; MAFA; PKNOX1; EPAS1; MEIS1; CLCF1; TENM3; ADD2; SDCBP2|
|transcription corepressor activity||ATF7IP; MECP2; HDAC4; NOC2L; NAB2; RYBP; HEYL; POU1F1; SKOR1B; NCOR2|
|transcription factor activity, sequence-specific DNA binding||MAFGA; DLX2; ZNF23; ELF2A; ARNTL1B; CTBP1; MNX2A; DMRTA2; ZNF75D; EGR4|
zhx1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with zhx1 here. Most of them are supplied by our site. Hope this information will be useful for your research of zhx1.
DNMT3B; ZHX2; ATXN1; NR3C1; PSMD11; BHLHE40; TNFRSF10C; PEX14; PRPF40A; IDH1