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ZNF10

Official Full Name

zinc finger protein 10
Overview

The protein encoded by this gene contains a C2H2 zinc finger, and has been shown to function as a transcriptional repressor. The Kruppel-associated box (KRAB) domain of this protein is found to be responsible for its transcriptional repression activity. RING finger containing protein TIF1 was reported to interact with the KRAB domain, and may serve as a mediator for the repression activity of this protein.
Synonyms

ZNF10; zinc finger protein 10; zinc finger protein 10 (KOX 1); KOX1; Zinc finger protein KOX1;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	ZNF10-7941H	Recombinant Human ZNF10 protein, His & T7-tagged	E.coli	His&T7	Met1~Asp244	Inquiry
Human	ZNF10-147HCL	Recombinant Human ZNF10 293 Cell Lysate	HEK293	Non		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

ZNF10 involved in several pathways and played different roles in them. We selected most pathways ZNF10 participated on our site, such as Gene Expression, Generic Transcription Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ZNF10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Gene Expression	ZNF561;RRAGA;SNAPC5;GATAD2AB;ZNF493;ZNF490;PIWIL4;GPR19;ZNF485
Generic Transcription Pathway	RRAGA;ZNF3;ZNF668;ZKSCAN4;ZNF729;ZNF257;RNF111;ZNF554;ZNF227

ZNF10 has several biochemical functions, for example, DNA binding, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZNF10 itself. We selected most functions ZNF10 had, and list some proteins which have the same functions with ZNF10. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	NFYA;ZNF286A;VENT;GSX1;ZFP654;MB21D2;SSRP1A;LIG3;ETV5B
metal ion binding	ARHGEF1A;ATP2A3;ZBTB22;XIRP2;SEMG1;GLIS2B;AGAP2;ZZEF1;SP6
protein binding	TNFRSF1B;KCNK16;KCNE2;PPP1R2P3;TEX19.1;EXOC4;WDR11;BCAM;AP5S1

ZNF10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZNF10 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZNF10.

TRIM28; Trim24; NDEL1

Research Area

Horn, F; Habekuss, A; et al. Genes involved in barley yellow dwarf virus resistance of maize. THEORETICAL AND APPLIED GENETICS 127:2575-2584(2014).

Enders, A; Short, A; et al. Zinc-finger protein ZFP318 is essential for expression of IgD, the alternatively spliced Igh product made by mature B lymphocytes. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111:4513-4518(2014).