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ZNF397

Official Full Name

zinc finger protein 397
Overview

This gene encodes a protein with a N-terminal SCAN domain, and the longer isoform contains nine C2H2-type zinc finger repeats in the C-terminal domain. The protein localizes to centromeres during interphase and early prophase, and different isoforms can repress or activate transcription in transfection studies. Multiple transcript variants encoding different isoforms have been found for this gene. Additional variants have been described, but their biological validity has not been determined.
Synonyms

ZNF397; zinc finger protein 397; zinc finger protein 47 , ZNF47; MGC13250; ZSCAN15; zinc finger protein 47; zinc finger and SCAN domain-containing protein 15; ZNF47; AI461664; 2810411K16Rik; 6720480F11Rik;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rhesus Macaque

Source

E.coli
HEK293
HEK293T
Mammalian Cell

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	ZNF397-3846H	Recombinant Human ZNF397, His-tagged	E.coli	His	1-275aa	$319 / 25μg
Human	ZNF397-78HCL	Recombinant Human ZNF397 293 Cell Lysate	HEK293	Non		Inquiry
Human	ZNF397-2374H	Recombinant Human ZNF397 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc&DDK		Inquiry
Mouse	Zfp397-7090M	Recombinant Mouse Zfp397 Protein, Myc/DDK-tagged	HEK293T	Myc&DDK		Inquiry
Rhesus Macaque	ZNF397-5329R	Recombinant Rhesus monkey ZNF397 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	ZNF397-5142R	Recombinant Rhesus Macaque ZNF397 Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Rhesus Macaque	ZNF397-5142R-B	Recombinant Rhesus Macaque ZNF397 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

ZNF397 involved in several pathways and played different roles in them. We selected most pathways ZNF397 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ZNF397 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

ZNF397 has several biochemical functions, for example, metal ion binding, protein binding, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZNF397 itself. We selected most functions ZNF397 had, and list some proteins which have the same functions with ZNF397. You can find most of the proteins on our site.

Function	Related Protein
metal ion binding	WDFY3;AIFM4;ZFYVE21;ZNF784;ING5A;PRKCZ;ZNF577;MORC4;HIC1
protein binding	RCC1;SKA3;ORC2L;SLC25A46;ACP1;NPHP4;C10orf33;XRCC2;FASLG
sequence-specific DNA binding	NR4A1;VDR;ISL1L;ETV5A;DLX3B;FEV;GBX1;HOXB1;SHOX
transcription factor activity, sequence-specific DNA binding	HIST1H2AH;ZFP30;RFX8;CSRNP3;HOXB6B;HES6;GM239;PAX8;SALL4

ZNF397 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZNF397 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZNF397.

PRKAA2; LMO4; ZNF410; ZNF446

Research Area

Zhang, Y; Hu, W; et al. Cysteine 397 plays important roles in the folding of the neuron-restricted silencer factor/RE1-silencing transcription factor. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 414:309-314(2011).

Liu, JL; Rigolet, P; et al. The zinc finger motif of Escherichia coli RecQ is implicated in both DNA binding and protein folding. JOURNAL OF BIOLOGICAL CHEMISTRY 279:42794-42802(2004).