Intracellular Kinases
- Akt Isoforms
- AMPK (AMP-activated Protein Kinases)
- CaM Kinases
- Carbohydrate Kinases
- Casein Kinases
- Creatin Kinase
- Cyclin-Dependent Protein Kinases (CDKs)
- DGK Family
- DYRKs (Dual-specificity Tyrosine-[Y]-phosphorylation Regulated Kinases)
- ERK (Extracellular Signal-regulated Kinases)
- GRKs (G Protein-coupled Receptor Kinases)
- IkB Kinase (IKK)
- IRAK Family
- Jak Kinases
- JNK
- MAP3K
- Mitogen-Activated Protein Kinase Kinases (MEKs/MKKs)
- MSK
- p38 MAP Kinases
- PAK (p21-activated Kinases)
- PI 3-Kinases (Phosphoinositide 3-Kinases)
- PKA Isoforms
- PKC Isoforms
- Polo-like Kinases
- Ribosomal Protein S6 Kinases (RSK)
- Src Kinases
About Intracellular Kinases
Intracellular kinases comprise a large class of enzymes that phosphorylate target proteins, thereby regulating their activity, localization, and interactions within the cell. They are involved in a wide range of cellular processes, including cell growth, proliferation, differentiation, metabolism, and cell survival. Intracellular kinases transmit signals from extracellular stimuli to the nucleus and other cellular compartments, coordinating complex cellular responses.
Recent studies have greatly improved our understanding of intracellular kinases and their roles in various cellular processes. Studies have elucidated complex signaling pathways and regulatory mechanisms involving intracellular kinases, providing insights into their involvement with diseases such as cancer, neurodegenerative diseases, and inflammation. Novel kinase inhibitors and therapeutic strategies targeting specific intracellular kinases have also emerged as potential treatments for various diseases.
Classification of Intracellular Kinases
Intracellular kinases can be classified into several families based on their structural and functional characteristics. Some prominent families include:
Protein Kinase A (PKA) Family: PKA family members, including PKA and PKG, are cyclic nucleotide-dependent kinases involved in the regulation of numerous cellular processes, such as metabolism, gene expression, and cell signaling.
Protein Kinase C (PKC) Family: PKC family members play crucial roles in signal transduction pathways, regulating processes such as cell proliferation, differentiation, apoptosis, and immune responses.
Mitogen-Activated Protein Kinases (MAPKs) Family: MAPK family members, including ERK, JNK, and p38, are involved in diverse cellular processes, including cell growth, differentiation, inflammation, and stress responses.
Phosphoinositide 3-Kinase (PI3K) Family: PI3K family members participate in various cellular functions, including cell survival, growth, proliferation, and metabolism, by regulating signaling pathways, such as the PI3K/AKT/mTOR pathway.
Research Tools for Intracellular Kinases
Creative BioMart provides comprehensive resources for intracellular kinase research, including recombinant proteins, cell and tissue lysates, protein pre-coupled magnetic beads, and other product reagents, as well as customized services to support researchers with specific projects related to intracellular kinases. Below are the various categories of intracellular kinases, please click to see all related molecules/targets and research reagents.
Our Advantages
When choosing Creative BioMart for intracellular kinase research, you will benefit from:
High-Quality Products: Creative BioMart provides high-quality recombinant proteins, cell and tissue lysates, protein pre-coupled magnetic beads, and other assay kits validated for intracellular kinase research.
Customization Options: Creative BioMart offers custom services to meet researchers' specific requirements, including protein production, antibody development, and assay development.
Expert Technical Support: Creative BioMart's team of experienced scientists provides expert technical support to ensure researchers achieve optimal results in their intracellular kinase studies.
Prompt Delivery: Creative BioMart ensures timely delivery of products and services, enabling researchers to proceed with their studies without delays.
Competitive Pricing: Creative BioMart offers competitive pricing options, making their resources and services accessible to researchers with varying budgets.
Contact Us
Creative BioMart is a trusted partner for researchers studying intracellular kinases. Researchers can benefit from high-quality products, expert technical support, customization options, and competitive pricing. Please contact us to explore the resources and services available for intracellular kinase research.
