ABCA4 Protein, ATP-binding cassette, sub-family A (ABC1), member 4

ABCA4

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ABCA4

Official Full Name ATP-binding cassette, sub-family A (ABC1), member 4
Background ATP-binding cassette, sub-family A (ABC1), member 4, also known as ABCA4 or ABCR, is a protein which in humans is encoded by the ABCA4 gene.
Synonyms FFM;RMP;ABCR;RP19;STGD;ABC10;ARMD2;CORD3;STGD1;FLJ17534;DKFZp781N1972;retinal-specific ATP-binding cassette transporter;
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ABCA4-033H Recombinant Human ABCA4 Protein, GST-Tagged Wheat Germ GST
    Human ABCA4-8115H Recombinant Human ABCA4 protein, His & T7-tagged E.coli His/T7
    Mouse ABCA4-1080M Recombinant Mouse ABCA4 Protein Mammalian Cell His

    ABCA4 involved in several pathways and played different roles in them. We selected most pathways ABCA4 participated on our site, such as ABC transporters, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABCA4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    ABC transporters ABCB4; ABCG2; ABCB10; ABCC5; Abca2; ABCC3; ABCA1B; TAP1; ABCB1LB; ABCB5

    ABCA4 has several biochemical functions, for example, ATP binding, ATPase activity, ATPase activity, coupled to transmembrane movement of substances. Some of the functions are cooperated with other proteins, some of the functions could acted by ABCA4 itself. We selected most functions ABCA4 had, and list some proteins which have the same functions with ABCA4. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding GLYCTK; ADCY8; PTK6B; NEK8; STK10; MAP3K11; MKNK2A; CLCN6; TOR2A; STRADA
    ATPase activity MYO9B; ATAD1; KIF3CB; HSPA5; PMS2; KIF4; EIF4A1A; KIF27; DNAH6; MLH3
    ATPase activity, coupled to transmembrane movement of substances ABCC9; ABCA5; ABCB3L1; Abca2; ABCC11; ABCD2; ABCA7; ABCD3; ABCG2; ABCC3
    cholesterol transporter activity APOA4A; ABCG1; CETP; APOE; STAR; APOA4; APOA1; ABCA1B; APOEA; ABCA1
    nucleotide binding MATR3; MRPL23; DNM1B; RHOGB; MXB; RBPMS2; ABCB1A; ADCY1B; RBM39A; TIAL1
    phospholipid transporter activity ABCA4; ABCA1B; MFSD2AA; CETP; OSBPL5; MFSD2AB; MFSD2A; ABCG1; ATP8B5; ABCA13
    phospholipid-translocating ATPase activity ATP8A1; ABCA4; ATP8B3; ATP9B; ATP11A; ATP10A; ATP11C; ATP9A; Atp8a2; ATP8B5
    transporter activity HIATL1; ATP5D; OCA2; SLC5A3A; Csn1s2b; STEAP2; HIAT1; TMEM184BA; AQP12B; SYN1

    ABCA4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABCA4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABCA4.

    Grassmann, F; Bergholz, R; et al. Common synonymous variants in ABCA4 are protective for chloroquine induced maculopathy (toxic maculopathy). BMC OPHTHALMOLOGY 15:-(2015).
    Puntel, A; Maeda, A; et al. Prolonged prevention of retinal degeneration with retinylamine loaded nanoparticles. BIOMATERIALS 44:103-110(2015).

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