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Recombinant Human ABCA4 protein, His & T7-tagged

Cat.No. : ABCA4-8115H
Product Overview : Recombinant Human ABCA4 aa. (Gly1398~Asn1727 (Accession # P78363)) fused with N-terminal His & T7 tag was produced in E. coli cells.
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  • Gene Information
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Source : E. coli
Species : Human
Tag : His & T7
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 40.7kDa.
Protein length : Gly1398~Asn1727 (Accession # P78363)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >90%
Characteristic : The isoelectric point is 7.7.
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage Buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : ABCA4 ATP binding cassette subfamily A member 4 [ Homo sapiens (human) ]
Official Symbol : ABCA4
Gene ID : 24
mRNA Refseq : NM_000350.2
Protein Refseq : NP_000341.2
UniProt ID : P78363

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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How are your recombinant ABCA4 proteins produced? 04/14/2023

Our recombinant ABCA4 proteins are produced in E. coli, Wheat Germ, or Mammalian Cell expression systems. And the product data sheet will provide you with specific information on how individual proteins were produced.

Can your ABCA4 protein product be used as a positive control? 04/14/2023

Our recombinant ABCA4 proteins have high purity and immunoreactivity, suitable for use as positive controls in, for example, ELISA, WB and other tests.

I would like to buy ABCA4 recombinant protein, is there any discount? 04/14/2023

Creative BioMart offers coupons for each new customer and runs promotions on important holidays. Follow our website for the latest promotions.

I have purchased your recombinant ABCA4 protein, what is its shelf life? 04/14/2023

Most recombinant proteins have a shelf life of one year. This guarantee is provided if they are kept under the optimal storage conditions described on the instruction. Please be careful to avoid repeated freezing and thawing.

Does His or GST tag affect ABCA4 protein activity? 04/14/2023

Protein tags may or may not affect protein activity. For some applications, His tags may not affect protein activity and therefore need not be removed. However, protein tags are useful for affinity purification or for a variety of other purposes. If you are concerned about tags interfering with protein activity, Creative BioMart can also offer tag-free recombinant ABCA4 protein customization services.

What diseases are ABCA4 mutation associated with? 04/14/2023

Mutations in the ABCA4 gene have been found in patients with Stargardt disease. In addition, its mutation are also associated with cone-rod dystrophy type 3, retinitis pigmentosa-19, early-onset severe retinal dystrophy, macular degeneration age-related 2, and fundus flavimaculatus.

Where is ABCA4 protein mainly expressed during physiological processes? 04/14/2023

ABCA4 is expressed exclusively in retinal photoreceptor cells and mediates the transport of the essential molecule atRAL across the photoreceptor cell membrane.

What is the molecular function of ABCA4? 04/14/2023

ABCA4 protein has the molecular function of translocase and is involved in biological processes such as sensory transduction, transport and vision.

Which gene encodes the ABCA4 protein? 04/14/2023

ABCA4 (ABCR, ARMD2, CORD3, FFM, RP19, STGD, STGD1).

What tags does your recombinant full-length ABCA4 use? 04/14/2023

Our ABCA4 protein products use His or GST tags.

Customer Reviews (3)

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Reviews
02/21/2021

    I purchased recombinant ABCA4 protein during the promotion. The price was very affordable and the product is of high quality and reliable, which saved me plenty of time and headaches.

    05/01/2020

      Your recombinant ABCA4 protein has helped me make some progress in understanding the pathogenesis of macular degeneration.

      02/01/2020

        I have been using your recombinant protein products and hope that the high quality standards and competitive prices will be maintained in the future.

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