|Official Full Name||abhydrolase domain containing 4|
|Background||Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine.|
|Synonyms||ABHD4; abhydrolase domain containing 4; abhydrolase domain-containing protein 4; FLJ12816; alpha/beta-hydrolase 4; lyso-N-acylphosphatidylethanolamine lipase; ABH4|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
ABHD4 involved in several pathways and played different roles in them. We selected most pathways ABHD4 participated on our site, such as Glycerophospholipid biosynthesis, Hydrolysis of LPE, Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABHD4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Glycerophospholipid biosynthesis||CHKA; CPNE6; ABHD3; SLC44A5B; AWAT2; CDS1; CHKB; PNPLA8; DGAT1B; AGPAT2|
|Hydrolysis of LPE||ABHD4|
|Metabolism||GPC5A; ETFA; PPM1K; SULT1C4; NFYAL; CYP27A1; FA2H; AMDHD1; HS3ST4; CEPT1A|
|Metabolism of lipids and lipoproteins||FAM213B; DHCR24; SREBF2; YAP1; ARSJ; STARD5; EBP; MED23; CYP8B2; ACOT11B|
|Phospholipid metabolism||PLBD1; SACM1L; CEPT1; PTPMT1; AWAT1; ABHD3; SACM1LB; SLC44A5B; ABHD4; SACM1LA|
ABHD4 has several biochemical functions, for example, carboxylic ester hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ABHD4 itself. We selected most functions ABHD4 had, and list some proteins which have the same functions with ABHD4. You can find most of the proteins on our site.
|carboxylic ester hydrolase activity||AADACL2; Cel; FAM135B; CES1; NCEH1A; LIPCA; ACOT12; PNPLA7; ACOT6; Aadacl3|
ABHD4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABHD4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABHD4.