ACSL1

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ACSL1

Official Full Name acyl-CoA synthetase long-chain family member 1
Background The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
Synonyms ACSL1; acyl-CoA synthetase long-chain family member 1; ACS1; LACS; FACL1; FACL2; LACS1; LACS2; long-chain-fatty-acid--CoA ligase 1; LACS 1; LACS 2; acyl-CoA synthetase 1; palmitoyl-CoA ligase 1; palmitoyl-CoA ligase 2; paltimoyl-CoA ligase 1; lignoceroyl-CoA synthase; long-chain acyl-CoA synthetase 1; long-chain acyl-CoA synthetase 2; long-chain fatty acid-CoA ligase 2; long-chain fatty-acid-coenzyme A ligase 1; fatty-acid-Coenzyme A ligase, long-chain 1; fatty-acid-Coenzyme A ligase, long-chain 2;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ACSL1-195H Recombinant Human ACSL1 Protein, GST-tagged Wheat Germ GST
    Human ACSL1-26479TH Recombinant Human ACSL1 Wheat Germ N/A
    Mouse ACSL1-1225M Recombinant Mouse ACSL1 Protein Mammalian Cell His
    Rat ACSL1-469R Recombinant Rat ACSL1 Protein Mammalian Cell His
    Chicken ACSL1-1950C Recombinant Chicken ACSL1 Mammalian Cell His

    ACSL1 involved in several pathways and played different roles in them. We selected most pathways ACSL1 participated on our site, such as Fatty acid biosynthesis, Fatty acid degradation, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACSL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Fatty acid biosynthesis ACSL1; ECHDC3; ECHDC2; ACSL4A; OLAH; ACSL3A; ACSL4; ACSL3; FASN; ACSL3B
    Fatty acid degradation ACADL; ACSBG2; ALDH3A2A; HADH; ACAA1; ACADSB; ACSL4A; ACADM; HADHB; ACOX3
    Metabolic pathways SGMS2; DHCR24; B3GNT2B; PLCZ1; CKMT2B; DAO.3; Akr1b3; GLB1; CES1; PAFAH1B1
    Fatty acid metabolism SCD; PECR; FADS2; ACSL1A; ELOVL5; HADHAB; ACAT1; ACADVL; ACSL4B; ACSL3A
    PPAR signaling pathway RXRGB; PPARA; ACADL; ACAA1A; RXRG; RXRAA; MMP1A; PPARDB; APOA1A; PPARG
    Peroxisome NOS2; CRATA; ACOX2; PEX19; ECH1; FAR2; AGPS; XDH; ACSL3; ACOX3
    Adipocytokine signaling pathway PPARA; SLC2A4; ACSBG2; PRKCQ; AKT2L; PTPN11A; NFKBIAB; LEPA; LEPB; PPARAB

    ACSL1 has several biochemical functions, for example, ATP binding, acetate-CoA ligase (ADP-forming) activity, catalytic activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ACSL1 itself. We selected most functions ACSL1 had, and list some proteins which have the same functions with ACSL1. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding PEX1; JAK2B; FGFR3; PI4K2A; INSRB; ERBB3; HK1; SMC1A; ATP2C1; RAD17
    acetate-CoA ligase (ADP-forming) activity ACSL1
    catalytic activity GNSA; SYN2B; GAD1B; AZIN1B; ACSL4A; PGAM1A; PKM; UQCRC2B; ASAH1; RDH7
    ligase activity RC3H2; UBE2I; UBR7; MARCH4; ZFP91; UBE2CBP; ITCH; RNF169; CPS1; NEDD4
    long-chain fatty acid-CoA ligase activity ACSL4; SLC27A3; SLC27A4; ACSL3; ACSL1; ACSBG2; SLC27A5; SLC27A1B; SLC27A2; ACSBG1
    nucleotide binding TRA2B; EEF1A1L2; LRGUK; IGF1RB; ACTC1B; D19ERTD386E; RBM28; HNRNPABB; EIF4BA; NUBP1

    ACSL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACSL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ACSL1.

    Pgrmc1; CYP2C2; Ephx1; Cyp2d10; Hsd11b1; Ywhae; Ywhaz; Fmo5

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