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ACSM1

  • Official Full Name

    acyl-CoA synthetase medium-chain family member 1

  • Synonyms

    ACSM1;acyl-CoA synthetase medium-chain family member 1;18049;ENSG00000166743;BUCS1;MACS1;16p12.3;MGC150532;acyl-coenzyme A synthetase ACSM1, mitochondrial;acyl-coenzyme A synthetase ACSM1, mitochondrial;Butyrate CoA ligase;butyrate--CoA ligase 1;lipoate-activating enzyme;butyryl Coenzyme A synthetase 1;butyryl-coenzyme A synthetase 1;medium-chain acyl-CoA synthetase;middle-chain acyl-CoA synthetase 1;EC 6.2.1.2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ACSM1-204H Recombinant Human ACSM1 Protein, GST-tagged Wheat Germ GST
Human ACSM1-203H Recombinant Human ACSM1 Protein, GST-tagged Wheat Germ GST
Human ACSM1-8165H Recombinant Human ACSM1 protein, His & T7-tagged E.coli His/T7 Ser370~Pro557 (Accession # Q08AH1)
Human ACSM1-9072HCL Recombinant Human ACSM1 293 Cell Lysate HEK293 N/A
Human ACSM1-806HF Recombinant Full Length Human ACSM1 Protein, GST-tagged In Vitro Cell Free System GST 577 amino acids
Mouse ACSM1-1230M Recombinant Mouse ACSM1 Protein Mammalian Cell His
Mouse ACSM1-274M-B Recombinant Mouse ACSM1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Acsm1-61M Recombinant Mouse Acsm1 Protein, His-tagged E.coli N-His Glu119-Val362
Mouse ACSM1-274M Recombinant Mouse ACSM1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Acsm1-62R Recombinant Rat Acsm1 Protein, His-tagged E.coli N-His Gly270-Glu520
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ACSM1 Related Articles

ACSM1 involved in several pathways and played different roles in them. We selected most pathways ACSM1 participated on our site, such as Amino Acid conjugation, Biological oxidations, Butanoate metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACSM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Amino Acid conjugationACSM1;GLYATL2;GLYATL1;GLYAT
Biological oxidationsADH7;SULT1B1;PRKRA;Sult2a6;ABHD14B;CYP11B1;ADH5;CYP2B6;SULT1ST5
Butanoate metabolismOXCT1B;ACSM3;ACSM5;ALDH5A1;HMGCL;OXCT1;EHHADH;ACAT1;BDH1
Conjugation of benzoate with glycineGLYATL2;GLYAT;ACSM1;GLYATL1
Conjugation of carboxylic acidsGLYATL2;GLYAT;ACSM1;GLYATL1
Conjugation of phenylacetate with glutamine
Metabolic pathwaysHSD17B12A;IMPA2;SAT2;PIGS;CHKB;NDUFA6;ATP6V0A1A;HIBADHB;GLS
MetabolismNUDT4A;SLC25A32A;SLC44A5B;NUDT3;LPA;OXSR1;AGL;SLC25A32;BCKDK

ACSM1 has several biochemical functions, for example, ATP binding, GTP binding, acyl-CoA ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ACSM1 itself. We selected most functions ACSM1 had, and list some proteins which have the same functions with ACSM1. You can find most of the proteins on our site.

Function Related Protein
ATP bindingCDKL1;HSPA12B;FARS2;CLCN4;CLK4B;ATP11C;TOR1;GPHN;PPP1CA
GTP bindingGIMAP5;RAB3C;RAB33BA;EEF2;RTKN;SEPT9;NPR1;ARL4D;RAB9B
acyl-CoA ligase activity
butyrate-CoA ligase activityACSM5;ACSM2B;AACS;ACSM1;ACSM3;PPP1CA;ACSM2;Acsm2a;ACSM4
fatty acid ligase activityACSM3;ACSM1
metal ion bindingNEURL3;ADH8A;TRIM35;CSGALNACT1;HAGHL;ADNP2;SUV39H1A;ZNF705A;KIN

ACSM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACSM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ACSM1.

q81sn0_bacan

Li, WJ; Ji, WD; et al. Genetic Association of ACSM1 Variation with Schizophrenia and Major Depressive Disorder in the Han Chinese Population. AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS 168:144-149(2015).
Gromov, P; Espinoza, JA; et al. FABP7 and HMGCS2 Are Novel Protein Markers for Apocrine Differentiation Categorizing Apocrine Carcinoma of the Breast. PLOS ONE 9:-(2014).
  • Q&As
  • Reviews

Q&As (10)

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What is the role of ACSM1 in the gut microbiome? 12/05/2021

Recent studies have shown that ACSM1 expression in the gut is associated with changes in the gut microbiome and may play a role in regulating the gut-brain axis.

How does ACSM1 expression change in response to exercise? 12/03/2021

ACSM1 expression has been shown to increase in response to exercise, which may help to increase the utilization of medium-chain fatty acids for energy.

How does ACSM1 activity affect exercise performance? 11/10/2021

ACSM1 activity has been shown to be important for the utilization of medium-chain fatty acids during exercise and may contribute to improved exercise performance.

How is ACSM1 expression regulated by circadian rhythms? 03/04/2021

ACSM1 expression is regulated by the circadian clock and may play a role in the regulation of metabolic processes.

What is the potential therapeutic value of targeting ACSM1? 04/20/2020

ACSM1 inhibition has been suggested as a potential therapeutic strategy for the treatment of metabolic disorders such as obesity, type 2 diabetes, and nonalcoholic fatty liver disease.

What post-translational modifications can affect ACSM1 protein function? 04/15/2020

Phosphorylation and acetylation have been shown to affect ACSM1 enzyme activity and may play a role in regulating fatty acid metabolism.

How does ACSM1 contribute to the development of breast cancer? 09/14/2019

Recent studies have shown that ACSM1 expression is increased in breast cancer cells and may play a role in promoting tumor growth and metastasis.

How does ACSM1 contribute to the development of nonalcoholic fatty liver disease (NAFLD)? 06/13/2019

Recent studies have shown that ACSM1 expression is increased in the liver of patients with NAFLD and may contribute to the development of this condition by promoting hepatic lipid accumulation.

How is ACSM1 expression regulated by epigenetic modifications? 01/18/2019

Recent studies have shown that DNA methylation and histone modifications can regulate ACSM1 gene expression, potentially playing a role in the development of metabolic disorders.

What is the role of ACSM1 in brown adipose tissue (BAT) function? 08/11/2018

Recent studies have shown that ACSM1 expression in BAT is associated with increased thermogenesis and energy expenditure.

Customer Reviews (5)

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Reviews
01/04/2022

    It performs exceptionally well in a variety of experimental applications, proving its broad utility.

    08/13/2021

      The price was competitive and fair, especially considering the high quality of the protein.

      04/29/2021

        The performance of this protein in my lab has been exceptional. It consistently yields robust and reproducible results, making it an invaluable tool for our research. Highly recommended!

        12/04/2019

          The protein's bioactivity is impressive. It induces the desired cellular response in our functional assays, proving its efficacy in our research.

          07/03/2019

            Budget-friendly protein without compromising on quality. Service was exceptional too.

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