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ACTL7B

Official Full Name

actin-like 7B
Overview

The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7B), and related gene, ACTL7A, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. Unlike ACTL7A, the ACTL7B gene is expressed predominantly in the testis, however, its exact function is not known.
Synonyms

ACTL7B; actin-like 7B; actin-like protein 7B; Tact1; MGC151194; Actin like 7 beta; Actin like 7B; Actin like protein 7B; MGC151192; OTTHUMP00000021867; OTTMUSP00000007742; RP11-3J11.2; RP23-48F4.1; t actin 1; actin-like 7-beta; actin-like-7-beta;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat

Source

HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
MYC
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	ACTL7B-225H	Recombinant Human ACTL7B Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	ACTL7B-226H	Recombinant Human ACTL7B Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	ACTL7B-9058HCL	Recombinant Human ACTL7B 293 Cell Lysate	HEK293	N/A		Inquiry
Human	ACTL7B-849HF	Recombinant Full Length Human ACTL7B Protein, GST-tagged	In Vitro Cell Free System	GST	415 amino acids	Inquiry
Mouse	ACTL7B-1247M	Recombinant Mouse ACTL7B Protein	Mammalian Cell	His		Inquiry
Mouse	Actl7b-525M	Recombinant Mouse Actl7b Protein, MYC/DDK-tagged	HEK293T	MYC/DDK		Inquiry
Mouse	ACTL7B-288M	Recombinant Mouse ACTL7B Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	ACTL7B-288M-B	Recombinant Mouse ACTL7B Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	ACTL7B-484R	Recombinant Rat ACTL7B Protein	Mammalian Cell	His		Inquiry
Rat	ACTL7B-140R-B	Recombinant Rat ACTL7B Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	ACTL7B-140R	Recombinant Rat ACTL7B Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry

Involved Pathway
Protein Function
Interacting Protein

ACTL7B involved in several pathways and played different roles in them. We selected most pathways ACTL7B participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ACTL7B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

ACTL7B has several biochemical functions, for example, structural constituent of cytoskeleton. Some of the functions are cooperated with other proteins, some of the functions could acted by ACTL7B itself. We selected most functions ACTL7B had, and list some proteins which have the same functions with ACTL7B. You can find most of the proteins on our site.

Function	Related Protein
structural constituent of cytoskeleton	SPTBN1;ARPC4;F-KER;ACTL6B;TUBA7L;ACTA1;NGS;TUBA2;ACTR2

ACTL7B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACTL7B here. Most of them are supplied by our site. Hope this information will be useful for your research of ACTL7B.