acy3
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  • Official Full Name
  • aspartoacylase (aminocyclase) 3
  • Background
  • Plays an important role in deacetylating mercapturic acids in kidney proximal tubules.
  • Synonyms
  • ACY3; aspartoacylase (aminocyclase) 3; aspartoacylase-2; ACY 3; HCBP1; MGC9740; 0610006H10Rik; AA3; ACY-3; ACY3_HUMAN; Acylase III; Aminoacylase 3; Aminoacylase III; Aminoacylase-3; ASPA2; Aspartoacylase (aminoacylase) 3; Aspartoacylase 2; AW107362; EC 3.5.1.-; EC 3.5.1.15; Hepatitis C virus core binding protein 1; Hepatitis C virus core-binding protein 1; MGC108859; RGD1305394; OTTHUMP00000235614; OTTHUMP00000235615
Cat.#:ACY3-3577HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ACY3, His-tagged
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Cat.#:ACY3-26720THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ACY3, His-tagged
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Cat.#:ACY3-164HTag:Myc|DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human ACY3 protein, MYC/DDK-tagged
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Cat.#:ACY3-263HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ACY3 Protein, GST-tagged
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Cat.#:ACY3-9361HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ACY3, GST-tagged
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Cat.#:ACY3-1268MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ACY3 Protein
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Cat.#:ACY3-498RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat ACY3 Protein
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Cat.#:ACY3-9043HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human ACY3 293 Cell Lysate
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Involved Pathway

ACY3 involved in several pathways and played different roles in them. We selected most pathways ACY3 participated on our site, such as Aflatoxin activation and detoxification, Biological oxidations, Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACY3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Aflatoxin activation and detoxification
CYP2Y3; CYP3A4; CYP2A13; PRKRA; CYP1A2; CYP3C4; ACY3.1; ACY3; CYP3C1; GGTLC1
Biological oxidations
FDX1L; ADH1C; DPEP1; FDXR; CYP1B1; ADH6; SLC35B2; ADH8B; POMCB; SULT1ST6
Metabolism
SAT1B; NFYBA; CTRB1; SLC25A14; PPM1LA; PPM1K; PTGR1; ACY3.2; PYGMB; ACOT8

Protein Function

ACY3 has several biochemical functions, for example, aminoacylase activity, hydrolase activity, acting on ester bonds, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ACY3 itself. We selected most functions ACY3 had, and list some proteins which have the same functions with ACY3. You can find most of the proteins on our site.
Function
Related Protein
Function aminoacylase activity
Related Protein DARS; ASPA; ACY1; ACY3; CAT
Function hydrolase activity, acting on ester bonds
Related Protein ASPA; RAG1; SMFN; ACY3.2; LIPM; PGAP3; ACY3.1; LIPN; LIPK; ENDOU2
Function identical protein binding
Related Protein SHANK1; ANXA4; ADIPOR2; KCNRG; TNF; PRMT8; SEPHS1; NONO; CALHM1; C14orf166
Function metal ion binding
Related Protein HE2; MOCS1; ZNF354A; KLF1; ADSSL; OAS2; GCM2; ZNF558; ATF7A; ZFP641
Function molecular_function
Related Protein NYX; DOPEY2; TMED1B; PDK3B; ZNF614; PSTPIP1B; GJD4; FNDC7; COMMD4; RSRC1
Function protein binding
Related Protein RPS19BP1; RAB2A; CRTC2; MAPK3; FOXO3; NUP35; IL13; ZNF580; ANP32A; MAGI2

Interacting Protein

ACY3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACY3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ACY3.
GORASP2; PMM2; PIAS2; ASPA; NOTCH2NL

ACY3 Related Articles

Hiltunen, TP; Donner, KM; et al. Pharmacogenomics of Hypertension: A Genome-Wide, Placebo-Controlled Cross-Over Study, Using Four Classes of Antihypertensive Drugs. JOURNAL OF THE AMERICAN HEART ASSOCIATION 4:-(2015).
Rise, ML; Nash, GW; et al. Variation in embryonic mortality and maternal transcript expression among Atlantic cod (Gadus morhua) broodstock: A functional genomics study. MARINE GENOMICS 18:3-20(2014).