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ACY3

  • Official Full Name

    aspartoacylase (aminocyclase) 3

  • Overview

    Plays an important role in deacetylating mercapturic acids in kidney proximal tubules.
  • Synonyms

    ACY3; aspartoacylase (aminocyclase) 3; aspartoacylase-2; ACY 3; HCBP1; MGC9740; 0610006H10Rik; AA3; ACY-3; ACY3_HUMAN; Acylase III; Aminoacylase 3; Aminoacylase III; Aminoacylase-3; ASPA2; Aspartoacylase (aminoacylase) 3; Aspartoacylase 2; AW107362; EC 3.5.1.-; EC 3.5.1.15; Hepatitis C virus core binding protein 1; Hepatitis C virus core-binding protein 1; MGC108859; RGD1305394; OTTHUMP00000235614; OTTHUMP00000235615;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ACY3-164H Recombinant Human ACY3 protein, MYC/DDK-tagged HEK293 Myc/DDK
Human ACY3-26720TH Recombinant Human ACY3, His-tagged E.coli His 319 amino acids
Human ACY3-9361H Recombinant Human ACY3, GST-tagged E.coli GST 1-319a.a.
Human ACY3-3577H Recombinant Human ACY3, His-tagged E.coli His
Human ACY3-263H Recombinant Human ACY3 Protein, GST-tagged Wheat Germ GST
Human ACY3-9043HCL Recombinant Human ACY3 293 Cell Lysate HEK293 N/A
Human ACY3-4301H Recombinant Human ACY3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human ACY3-837HF Recombinant Full Length Human ACY3 Protein, GST-tagged In Vitro Cell Free System GST 319 amino acids
Mouse ACY3-1268M Recombinant Mouse ACY3 Protein Mammalian Cell His
Mouse ACY3-300M-B Recombinant Mouse ACY3 Protein Pre-coupled Magnetic Beads HEK293
Mouse ACY3-300M Recombinant Mouse ACY3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Acy3-1524M Recombinant Mouse Acy3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat ACY3-498R Recombinant Rat ACY3 Protein Mammalian Cell His
Rat ACY3-154R Recombinant Rat ACY3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat ACY3-154R-B Recombinant Rat ACY3 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ACY3 Related Articles

ACY3 involved in several pathways and played different roles in them. We selected most pathways ACY3 participated on our site, such as Aflatoxin activation and detoxification, Biological oxidations, Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACY3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Aflatoxin activation and detoxificationACY3.2;DPEP2;CYP3C4;CYP1A2;GGTLC1;GGT6;ACY3.1;CYP2Y3;CYP3A5
Biological oxidationsCYP2Y3;CYP1B1;SLC26A2;ADH1B;POMCB;CYP27A1;CYP2A13;CYP2J2;CYP2K18
MetabolismCOX16;ARSI;CYGB;ADSSL1;EBP;SLC46A1;CERS4A;MED20;CYP2U1

ACY3 has several biochemical functions, for example, aminoacylase activity, hydrolase activity, acting on ester bonds, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ACY3 itself. We selected most functions ACY3 had, and list some proteins which have the same functions with ACY3. You can find most of the proteins on our site.

Function Related Protein
aminoacylase activityDARS;ACY3;ASPA;CAT;ACY1
hydrolase activity, acting on ester bondsLIPM;PGAP3;ACY3.1;RAG1;ENDOU2;ESD;ACY3;IAH1;CES1C
identical protein bindingNISCH;SIRT1;MUL1;Serpina1c;PARP1;PTPRG;IRF3;LZTFL1;GBP5
metal ion bindingZNF483;ZNF763;ISL2A;GTF3A;PPM1F;NRXN3A;NME6;LIAS;AMY1B
molecular_functionARHGEF39;NPRL3;PHGR1;CPNE2;SSX2IPA;LEPRE1;BCL7BB;TSPAN32;TIFAB
protein bindingCDCA5;DOK2;CHORDC1;GPKOW;SYT17;DNAJA4;MAL2;FAM64A;USH2A

ACY3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACY3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ACY3.

GORASP2; PMM2; PIAS2; ASPA; NOTCH2NL

Hiltunen, TP; Donner, KM; et al. Pharmacogenomics of Hypertension: A Genome-Wide, Placebo-Controlled Cross-Over Study, Using Four Classes of Antihypertensive Drugs. JOURNAL OF THE AMERICAN HEART ASSOCIATION 4:-(2015).
Rise, ML; Nash, GW; et al. Variation in embryonic mortality and maternal transcript expression among Atlantic cod (Gadus morhua) broodstock: A functional genomics study. MARINE GENOMICS 18:3-20(2014).
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