ADAM19 Protein, ADAM metallopeptidase domain 19


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Official Full Name ADAM metallopeptidase domain 19
Background This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has been demonstrated to be an active metalloproteinase, which may be involved in normal physiological processes such as cell migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. It is proposed to play a role in pathological processes, such as cancer, inflammatory diseases, renal diseases, and Alzheimers disease. [provided by RefSeq, May 2013]
Synonyms ADAM19; ADAM metallopeptidase domain 19; MLTNB; FKSG34; MADDAM; disintegrin and metalloproteinase domain-containing protein 19; ADAM 19; meltrin-beta; metalloprotease-disintegrin meltrin beta; metalloprotease and disintegrin dendritic antigen marker; a disintegrin and metalloproteinase domain 19 (meltrin beta);
    • Species :
    • Chicken
    • Human
    • Mouse
    • Source :
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ADAM19-9038HCL Recombinant Human ADAM19 293 Cell Lysate HEK293 N/A
    Mouse ADAM19-1281M Recombinant Mouse ADAM19 Protein Mammalian Cell His
    Chicken ADAM19-4129C Recombinant Chicken ADAM19 Mammalian Cell His

    ADAM19 involved in several pathways and played different roles in them. We selected most pathways ADAM19 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ADAM19 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    ADAM19 has several biochemical functions, for example, SH3 domain binding, metalloendopeptidase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADAM19 itself. We selected most functions ADAM19 had, and list some proteins which have the same functions with ADAM19. You can find most of the proteins on our site.

    Function Related Protein
    SH3 domain binding NCKIPSD; RAD9A; GRIK5; SH3BP5L; DOCK1; LANCL1; WIPF3; ITM2B; PLSCR4; PLSCR1
    metalloendopeptidase activity ADAM17A; ADAM23; ADAMTS15A; ADAM10B; ADAM5; ADAM22; ADAMTS2; ZMPSTE24; ADAM33; BMP1
    zinc ion binding TCEA2; BAZ2B; ZFP276; RNF150; RNF25; MYLIP; AGBL4; LIN28A; ZCCHC17; ADH8A

    ADAM19 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADAM19 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADAM19.

    ABI2; UBC; ESF1

    Dijkstra, A; Postma, DS; et al. Expression of ADAMs ("a disintegrin and metalloprotease") in the human lung. VIRCHOWS ARCHIV 454:441-449(2009).
    Bu, SM; Yang, YJ; et al. Developmental and-hormonal regulation of meltrin beta (ADAM19) expression in mouse testes during embryonic and postnatal life. LIFE SCIENCES 79:2112-2118(2006).

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