ADCY3 Protein, adenylate cyclase 3


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Official Full Name adenylate cyclase 3
Background This gene encodes adenylyl cyclase 3 which is a membrane-associated enzyme and catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This protein appears to be widely expressed in various human tissues and may be involved in a number of physiological and pathophysiological metabolic processes.
Synonyms ADCY3; adenylate cyclase 3; adenylate cyclase type 3; AC3; Adenylate cyclase type III; AC-III; adenylyl cyclase 3; ATP pyrophosphate-lyase 3; adenylyl cyclase, type III; adenylate cyclase, olfactive type
    • Species :
    • Human
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • E.Coli or Yeast
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ADCY3-3173H Recombinant Human ADCY3, His-tagged E.Coli or Yeast His
    Human ADCY3-328H Recombinant Human ADCY3 Protein, GST-tagged Wheat Germ GST
    Human ADCY3-6925H Recombinant Human ADCY3 protein, His & T7-tagged E.coli His/T7
    Human ADCY3-9021HCL Recombinant Human ADCY3 293 Cell Lysate HEK293 N/A
    Rat Adcy3-3174R Recombinant Rat Adcy3, His-tagged E.Coli or Yeast His
    Zebrafish ADCY3-7540Z Recombinant Zebrafish ADCY3 Mammalian Cell His

    ADCY3 involved in several pathways and played different roles in them. We selected most pathways ADCY3 participated on our site, such as Activation of GABAB receptors, Activation of NMDA receptor upon glutamate binding and postsynaptic events, Adenylate cyclase activating pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADCY3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Activation of GABAB receptors ADCY7; KCNJ3; ADCY9; ADCY6; ADCY8; ADCY1; KCNJ12; GNGT2B; GNB3A; KCNJ6
    Activation of NMDA receptor upon glutamate binding and postsynaptic events AKAP9; CREB1; SLC14A2; CAMKK1B; ADCY3; CREB1B; PDPK1A; ADCY8; NETO2; NEFLB
    Adenylate cyclase activating pathway ADCY1; ADCY3; ADCY8; ADCY6; ADCY7; ADCY9
    Adenylate cyclase inhibitory pathway ADCY8; ADCY7; ADCY6; ADCY9; ADCY3; ADCY1
    Adrenergic signaling in cardiomyocytes ADCY8; CACNA1D; CACNB4A; ADRA1D; KCNQ1; PIK3R2; PIK3R1; MAPK12; PPP2R5EA; CALM1A
    Aldosterone synthesis and secretion CACNA1H; ADCY3; CREB3; NR4A1; ADCY1; PRKCB; CALM1; DDX1; AGTR1A; PLCB1
    Aquaporin-mediated transport MIP; AQP3B; AQP1A.1; GNB3B; ADCY3; AQP10A; AQP3A; AQP1A.2; MIPA; ADCY7
    Bile secretion SLC22A1; ABCC2; NCEH1; Abcb1b; AQP4; CFTR; SLC10A1; NR0B2; ADCY6; SLC51A

    ADCY3 has several biochemical functions, for example, ATP binding, adenylate cyclase activity, calcium- and calmodulin-responsive adenylate cyclase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ADCY3 itself. We selected most functions ADCY3 had, and list some proteins which have the same functions with ADCY3. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding PC; P2RY2; SARS; FGFR2; MAPK8; ATP9A; OASL2; ABCA9; MAP2K3; IARS2
    adenylate cyclase activity ADCY1A; GNAS; ADCY3; ADCY1; ADCY8; ADCY9; ADCY2B; ADCY1B; ADCY7; ADCY6
    calcium- and calmodulin-responsive adenylate cyclase activity ADCY8; ADCY3; ADCY1; ADCY6
    calmodulin binding CAMSAP1L1; KCNQ1; ITPKB; REM1; NOS3; CAMK4; MAPKAPK2A; DCX; CALD1B; KCNN1B
    metal ion binding RAD50; HGD; PPM1DA; FHL2A; ZNF669; RNF34B; KMT2A; ZFP513; TRIM50; ZFP385C

    ADCY3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADCY3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADCY3.


    Sebo, P; Osicka, R; et al. Adenylate cyclase toxin-hemolysin relevance for pertussis vaccines. EXPERT REVIEW OF VACCINES 13:1215-1227(2014).
    Pravetoni, M; Pentel, PR; et al. Effects of an Oxycodone Conjugate Vaccine on Oxycodone Self-Administration and Oxycodone-Induced Brain Gene Expression in Rats. PLOS ONE 9:-(2014).

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