|Official Full Name||adenylate cyclase 6|
|Background||This gene encodes adenylate cyclase 6, which is a membrane-associated enzyme and catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). The expression of this gene is found in normal thyroid and brain tissues, as well as some tumors; and its expression is significantly higher in one hyperfunctioning thyroid tumor than in normal thyroid tissue. Alternative splicing generates 2 transcript variants.|
|Synonyms||ADCY6; adenylate cyclase 6; adenylate cyclase type 6; AC6; ACVI; ADCY 6; ADCYB; Adenylate cyclase type VI; ATP pyrophosphate lyase 6; Ca(2+) inhibitable adenylyl cyclase; DKFZp779F075; EC 188.8.131.52; KIAA0422; adenylyl cyclase 6; ATP pyrophosphate-lyase 6; ca(2+)-inhibitable adenylyl cyclase|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
ADCY6 involved in several pathways and played different roles in them. We selected most pathways ADCY6 participated on our site, such as Activation of GABAB receptors, Adenylate cyclase activating pathway, Adenylate cyclase inhibitory pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADCY6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Activation of GABAB receptors||ADCY7; ADCY6; ADCY9; KCNJ9; KCNJ5; KCNJ3; KCNJ10; KCNJ12; GNB3B; KCNJ2|
|Adenylate cyclase activating pathway||ADCY6; ADCY3; ADCY9; ADCY8; ADCY1; ADCY7|
|Adenylate cyclase inhibitory pathway||ADCY1; ADCY8; ADCY7; ADCY9; ADCY6; ADCY3|
|Adrenaline,noradrenaline inhibits insulin secretion||GNB5; GNB5A; GNB5B; GNB3A; ADCY6; ADRA2C; GNB3B; ADRA2A|
|Adrenergic signaling in cardiomyocytes||PIK3R5; CALM2B; PPP1CBL; SCN1BA; MYH7; ADCY3; ATP1A2A; ATP1A1B; ADRB3A; PPP2R5B|
|Aldosterone synthesis and secretion||PRKD2; PRKACB; CAMK2G; HSD3B1; ADCY9; PRKCG; CREB5; ATF4; ORAI1; GNA11|
|Aquaporin-mediated transport||MIPA; MIPB; AQP10; AQP3A; AQP10B; AQP1A.2; ADCY1; AQP10A; GNB3B; AQP8A.1|
|Bile secretion||GNAS; SLCO1A4; Abcb1b; LDLR; SLC2A1; SLC5A1; SULT2A1; SLC9A1; SLCO1A5; AQP4|
ADCY6 has several biochemical functions, for example, ATP binding, adenylate cyclase activity, calcium- and calmodulin-responsive adenylate cyclase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ADCY6 itself. We selected most functions ADCY6 had, and list some proteins which have the same functions with ADCY6. You can find most of the proteins on our site.
|ATP binding||CKMT2A; KIF3B; PTK2BB; KIF5AA; ATP2A3; DDX24; NMRK2; CHD9; MLH1; SIK3|
|adenylate cyclase activity||ADCY1B; ADCY7; ADCY1; ADCY1A; ADCY8; ADCY9; Adcy4; ADCY6; ADCY3; GNAS|
|calcium- and calmodulin-responsive adenylate cyclase activity||ADCY1; ADCY3; ADCY8; ADCY6|
|metal ion binding||ADO; STK32C; ENDOU2; NR2F5; COX4I2; KDM6A; FAHD2A; ZNF556; METAP1; ADPGK|
|protein binding||CALM2; MAPRE2; KIF20B; NPDC1; HTATIP2; FRMD6; SPEG; PSMB4; C18orf1; BRCA1|
|protein kinase binding||SPDYA; SHC1; DCX; CDKN2B; AXIN1; GRIN2A; USP37; PLK1S1; PPP1R12C; GATA6|
|scaffold protein binding||SHANK1; DSP; SHANK3; NLRP1; ADCY6; TREM1; GRIN2A; KRT15; CAV2; SRC|
ADCY6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADCY6 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADCY6.