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ADM2

  • Official Full Name

    adrenomedullin 2

  • Synonyms

    ADM2;adrenomedullin 2;28898;ENSG00000128165;AM2;dJ579N16.4;22q13.33;FLJ21135;ADM2;ADM2;intermedin;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E.coli
  • E.Coli or Yeast
  • HEK293
  • Mammalian Cell
  • Protein Conjugation
  • His
  • His (Fc)
  • Avi
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ADM2-898H Recombinant Human ADM2 Mammalian Cell His
Human ADM2-2433H-B Recombinant Human ADM2 Protein Pre-coupled Magnetic Beads HEK293
Human ADM2-86H Recombinant Human ADM2 Protein, His-tagged E.coli N-His Thr101-Tyr147
Human ADM2-2433H Recombinant Human ADM2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human ADM2-2779H Recombinant Human ADM2 Protein, His-tagged, OVA Conjugated Protein Conjugation N-His Gln126-Asp140
Mouse ADM2-1366M Recombinant Mouse ADM2 Protein Mammalian Cell His
Mouse ADM2-352M-B Recombinant Mouse ADM2 Protein Pre-coupled Magnetic Beads HEK293
Mouse ADM2-352M Recombinant Mouse ADM2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Adm2-3203R Recombinant Rat Adm2, His-tagged E.Coli or Yeast His 146
Rat ADM2-531R Recombinant Rat ADM2 Protein Mammalian Cell His
Rat ADM2-187R Recombinant Rat ADM2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat ADM2-187R-B Recombinant Rat ADM2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque ADM2-251R Recombinant Rhesus monkey ADM2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque ADM2-79R Recombinant Rhesus Macaque ADM2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque ADM2-79R-B Recombinant Rhesus Macaque ADM2 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

ADM2 involved in several pathways and played different roles in them. We selected most pathways ADM2 participated on our site, such as Calcitonin-like ligand receptors, Class B/2 (Secretin family receptors), G alpha (s) signalling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADM2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Calcitonin-like ligand receptorsRAMP1;ADM2;RAMP2;CALCA;ADM2A;ADM;RAMP3;CALCB;CALCRL
Class B/2 (Secretin family receptors)SETD6;FZD10;GCGA;EMR2;ADCYAP1R1;ADM2A;GHRH;EMR3;CRH
G alpha (s) signalling eventsRLN2;GCGB;CRHR2;CRHR1;RLN3;ADCYAP1B;PTHLHA;INSL3;DRD5
GPCR downstream signalingCHRM1;ARHGEF3;HEBP1;NPB;CRH;OPN4B;PROKR2;RGS17;TAS2R3
GPCR ligand bindingCASR;RLN3A;CCRL2;NPS;QRFPR;GPR55A;CCR9;CXCL13;EDNRA
Signal TransductionNEDD8L;GPR65;DISP2;GPR31B;RXFP2B;USP34;LIN7B;ARHGAP15;OPN4A
Signaling by GPCRUTS2;RGS7;OPN4A;SOUL3;RCA2.1;PRLH;CCL35.1;ZFPM2B;KISS1

ADM2 has several biochemical functions, for example, hormone activity, protein complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADM2 itself. We selected most functions ADM2 had, and list some proteins which have the same functions with ADM2. You can find most of the proteins on our site.

Function Related Protein
hormone activityLRSAM1;UTS2;MLN;PRLH;EDN3;CSH1;FSD1;AVP;CGA
protein complex bindingTUBB;ERCC6;GIT1;MAPK8IP2;CEBPA;CFLAR;VPS28;DRD1A;PRMT5

ADM2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADM2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADM2.

  • Q&As
  • Reviews

Q&As (9)

Ask a question
Are ADM2 agonists currently available for clinical use? 03/05/2022

ADM2 agonists are still in the experimental stage and are not yet available for clinical use. However, several drug candidates are currently being evaluated in preclinical studies and clinical trials, and may eventually be developed as new therapies for the treatment of pain and other disorders.

How are ADM2 proteins involved in the regulation of pain? 07/10/2021

ADM2 proteins have been implicated in the regulation of pain perception. ADM2 has been shown to decrease pain sensitivity in animal models of chronic pain, and ADM2 agonists may be potential treatments for chronic pain conditions.

Can ADM2 agonists be used to treat anxiety and depression? 01/27/2021

There is some evidence to suggest that ADM2 agonists may have therapeutic potential in the treatment of anxiety and depression. However, more research is needed to determine the safety and efficacy of ADM2 agonists for these conditions.

How are ADM2 proteins being studied for potential therapies for cardiovascular disease? 11/30/2020

ADM2 proteins are being studied for potential therapies for cardiovascular disease because of their vasodilatory and cardioprotective effects. ADM2 agonists, which mimic the activity of ADM2, are being developed as potential treatments for hypertension, heart failure, and other cardiovascular disorders.

How do ADM2 proteins interact with the immune system? 03/25/2020

ADM2 proteins can interact with the immune system in several ways. ADM2 has been shown to modulate the activity of immune cells, including T cells, B cells, and macrophages. ADM2 can promote the production of anti-inflammatory cytokines and inhibit the production of pro-inflammatory cytokines.

How are ADM2 agonists different from opioids as painkillers? 08/08/2019

Unlike opioids, ADM2 agonists do not bind to opioid receptors and therefore do not produce the same side effects associated with opioid use, such as addiction and respiratory depression. ADM2 agonists may offer a safer alternative for the management of chronic pain.

How might ADM2 agonists impact the opioid epidemic? 04/13/2019

ADM2 agonists could have a significant impact on the opioid epidemic by providing a safer alternative for pain management. Unlike opioids, ADM2 agonists do not produce the same addictive effects, respiratory depression, or risk of overdose. By providing a non-addictive alternative for pain management, ADM2 agonists could help reduce the number of people who become addicted to opioids. Additionally, ADM2 agonists could potentially be used to help people who are already addicted to opioids to manage their pain without increasing their risk of overdose or other adverse effects.

Are there any side effects associated with ADM2 agonists? 04/01/2017

There have been no reported side effects associated with ADM2 agonists in clinical trials to date. However, as with any new drug, long-term safety and efficacy will need to be established in larger clinical studies.

Can ADM2 proteins be used as a biomarker for sepsis? 07/03/2016

ADM2 proteins have been studied as a potential biomarker for sepsis, a life-threatening condition that occurs when the body's immune response to infection becomes dysregulated. ADM2 levels have been shown to be elevated in patients with sepsis, and may be useful for diagnosing and monitoring the condition.

Customer Reviews (4)

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Reviews
08/28/2019

    The manufacturer's attention to detail in the protein's production process is evident, and I am confident that this product will provide me with accurate and dependable data.

    06/17/2019

      the unparalleled technical support provided by the manufacturer has given me the confidence that any challenges I may encounter can be swiftly and effectively resolved.

      07/30/2018

        the purity and consistency of the ADM2 protein have exceeded my expectations, ensuring that my experiments will yield reliable and reproducible results.

        01/23/2017

          After conducting extensive research, I have determined that ADM2 protein is of exceptional quality and will undoubtedly meet all of my experimental requirements.

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