AKAP5 Protein, A kinase (PRKA) anchor protein 5

AKAP5

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AKAP5

Official Full Name A kinase (PRKA) anchor protein 5
Background AKAPs (A-kinase anchoring proteins), as their name implies, are a family of scaffolding proteins that bind regulatory subunits of Protein Kinase A (PKA) thus localizing PKA activity to distinct regions of the cell (1). Beyond a common amphipathic alpha he
Synonyms AKAP5; A kinase (PRKA) anchor protein 5; A-kinase anchor protein 5; AKAP75; AKAP79; AKAP-5; AKAP 79; A-kinase anchor protein 79 kDa; A-kinase anchor protein, 79kDa; A-kinase anchoring protein 75/79; cAMP-dependent protein kinase regulatory subunit II high
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.Coli or Yeast
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human AKAP5-23H Recombinant Human AKAP5, His-tagged HEK293 His
    Human AKAP5-3030H Recombinant Human AKAP5, His-tagged E.Coli or Yeast His
    Human AKAP5-401H Recombinant Human AKAP5 Protein, GST-tagged Wheat Germ GST
    Human AKAP5-714H Recombinant Human AKAP5 Mammalian Cell His
    Human AKAP5-8939HCL Recombinant Human AKAP5 293 Cell Lysate HEK293 N/A
    Mouse AKAP5-1479M Recombinant Mouse AKAP5 Protein Mammalian Cell His
    Rat Akap5-3029R Recombinant Rat Akap5, His-tagged E.Coli or Yeast His

    AKAP5 involved in several pathways and played different roles in them. We selected most pathways AKAP5 participated on our site, such as Calcium signaling in the CD4+ TCR pathway, G Protein Signaling Pathways, Glucagon-like Peptide-1 (GLP1) regulates insulin secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with AKAP5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Calcium signaling in the CD4+ TCR pathway JUNB; FKBP1A; BATF3; RCAN2; POU2F1; CSF2; CHP; RCAN1; AKAP5
    G Protein Signaling Pathways GNA13; GNGT2A; AKAP5; Akap2; GNB5B; AKAP1B; AKAP8; AKAP4; Akap3; ARHGEF1A
    Glucagon-like Peptide-1 (GLP1) regulates insulin secretion GNB5B; KCNB1; KCNS3; KCNS3A; RAPGEF3; KCNC2; RAPGEF4; GCGA; GNB5A; GCGB
    Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity NSFB; GRIP1; PICK1; AKAP5; MYO6; CACNG2; NSFA; HAND2; CACNG3
    Integration of energy metabolism MARCKSB; ARL2; GNB5A; SYT5; KCNJ11; KCNC2; GNG13B; ARL2BP; KCNS3A; AKAP5
    Metabolism CYP2D6; LPA; GDF1; SULT4A1; ADH8B; VAPB; COX15; SGMS2; CD320; ACOT9
    Neuronal System HAND2; KCNJ1A.3; ABCC9; KCNA5; KCNH2A; KCND2; KCNS3A; GRIP1; SNAP25A; ARL6IP5B
    Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell CAMKK1B; NSFA; AKAP5; NCALDA; GRIP1; NSFB; DLG1L; CHRNA2; HAND2; GABRR2A

    AKAP5 has several biochemical functions, for example, G-protein coupled receptor binding, GABA receptor binding, actin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AKAP5 itself. We selected most functions AKAP5 had, and list some proteins which have the same functions with AKAP5. You can find most of the proteins on our site.

    Function Related Protein
    G-protein coupled receptor binding CORT; GNA13A; GNA15; GNA15.4; UTS2D; GNA13B; FYN; SFTPB; NPFF; PPY
    GABA receptor binding GABARAP; GABARAPA; GABRB1; GABRA5; PPP2CA; ARFGEF2; PLCL1; JAKMIP1; GABARAPL2; GABRG1
    actin binding SCIN; ACTN2B; WASF3B; HCLS1; KLHL20; CAPZA1B; PARK2; TNNI1; C19orf21; MYO1G
    adenylate cyclase binding AKAP6; CHRNA7; CALM3; CALM2; CALM1; ADRB2; ADCYAP1R1; AKAP12; AKAP5
    cadherin binding GNA13A; TRPC4; VCL; Fert2; CD46; NEO1; JUP; CTNNB1; FXYD5; CDK5R1
    calmodulin binding RGS16; SRY; MKNK2B; DDX5; CAMKV; MYO1G; ARPP21; PLCB3; CAMK2B; SPA17
    protein binding MAP2K3; MFF; NDUFS2; SYAP1; ABCA1; PRDM13; MTAP1A; HRG; PARP2; PLK2
    protein complex binding AP2A2; PGAM5; CPS1; VPS28; RBX1; CD2AP; UGT1A6A; PAFAH1B1; CRHR1; NASP
    protein domain specific binding TRP63; DVL2; CNOT1; RAPGEF3; EFS; RAB27A; ARR3; HSPA5; ARRB2; SORBS2
    protein kinase A binding Akap2; DACT2; AKAP5; RPS3; NBEA; AKAP14; Akap3; AKAP6; AKAP13; RARA
    protein kinase A regulatory subunit binding KCNQ1; AKAP8; C2orf88; AKAP7; PJA2; AKAP9; ARFGEF2; AKAP6; AKAP1; EZR
    protein kinase binding GRIN2A; PRC1; KCNH1; AXIN1; GATA6; SLC12A4; USP37; SYK; PDCD10; FGFR1OP
    protein phosphatase 2B binding AKAP1; PPP3CB; MYOZ2; AKAP5; BAD; ATP2B4; SLC9A1; SOD1

    AKAP5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AKAP5 here. Most of them are supplied by our site. Hope this information will be useful for your research of AKAP5.

    PRKAR2A; PRKACA; PRKACB; Kcnj2; KCNJ2; RXFP1; MRPL43; DERL1; 2_aha_camp; 8-aha-camp; 8-aha-omethyladenosine; HSPA8; SUV39H1; SLC25A12

    Hong, GE; Kim, JA; et al. Flavonoids Identified from Korean Scutellaria baicalensis Georgi Inhibit Inflammatory Signaling by Suppressing Activation of NF-kappa B and MAPK in RAW 264.7 Cells. EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE :-(2013).
    Huang, ZH; Somanath, PR; et al. Changes in intracellular distribution and activity of protein phosphatase PP1 gamma 2 and its regulating proteins in spermatozoa lacking AKAP4. BIOLOGY OF REPRODUCTION 72:384-392(2005).

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